SCHEMBL20071867

SCHEMBL20071867

Cc1cc2c(cc1C)N(c1ccccn1)C(=C1N(c3ccccn3)c3cc(C)c(C)cc3N1c1ccc(-c3ccc(N4C(=C5N(c6ccccn6)c6ccccc6N5c5ccccn5)N(c5ccccn5)c5ccccc54)nc3)cn1)N2c1ccccn1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.43
SLC11A2 P49281 6/20 0.37
KDM4E B2RXH2 1/20 0.37
CNR2 P34972 2/20 0.36
NOX4 Q9NPH5 1/20 0.36
NOX1 Q9Y5S8 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.35
IRAK4 Q9NWZ3 2/20 0.35
CHEK1 O14757 1/20 0.35
AURKA O14965 1/20 0.35
DAPK3 O43293 1/20 0.35
JAK2 O60674 1/20 0.35
PRKD3 O94806 1/20 0.35
MAP4K4 O95819 1/20 0.35
PAK4 O96013 1/20 0.35
ABL1 P00519 1/20 0.35
NTRK1 P04629 1/20 0.35
FYN P06241 1/20 0.35
CSF1R P07333 1/20 0.35
RET P07949 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18199843 0.87 SMN1; SMN2 (0.55) SMN1; SMN2SLC11A2KDM4ENOX4NOX1
SCHEMBL20062878 0.78 SMN1; SMN2 (0.53) SMN1; SMN2KDM4ENOX4NOX1CHEK1
SCHEMBL17952818 0.71 CHRNA7 (0.47) SMN1; SMN2CNR2FYNCYP1A2
SCHEMBL19343025 0.70 HTR3A (0.47) SMN1; SMN2KDM4EPDGFRBKDRFLT3
SCHEMBL17952821 0.67 CHRNA7 (0.40) SMN1; SMN2KDM4ECNR2
SCHEMBL18365154 0.67 SMN1; SMN2 (0.46) SMN1; SMN2KDM4ECYP17A1CYP1A2
SCHEMBL13296025 0.67 SMN1; SMN2 (0.53) SMN1; SMN2SLC11A2KDM4E
SCHEMBL18964725 0.66 SMN1; SMN2 (0.44) SMN1; SMN2KDM4ECHEK1AURKADAPK3
SCHEMBL20681916 0.66 SMN1; SMN2 (0.44) SMN1; SMN2KDM4E
SCHEMBL20062921 0.66 KDM4E (0.33) SMN1; SMN2KDM4EL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10541260-B2 Organic photoelectric conversion element, optical area sensor, imaging device, and imaging apparatus CANON KABUSHIKI KAISHA (JP) 2020-01-21 US disclosed
US-20180108691-A1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, OPTICAL AREA SENSOR, IMAGING DEVICE, AND IMAGING APPARATUS CANON KABUSHIKI KAISHA (JP) 2018-04-19 US disclosed