SCHEMBL20071965

SCHEMBL20071965

Cc1nc(N2c3ccccc3N(c3nc(C)c(C)s3)C2C2N(c3nc(C)c(C)s3)c3ccccc3N2c2nc(C)c(C)s2)sc1C

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.41
ALOX15 P16050 1/20 0.41
ALDH1A1 P00352 3/20 0.39
GAA P10253 3/20 0.39
NPC1 O15118 3/20 0.37
RAB9A P51151 3/20 0.37
PKM P14618 1/20 0.37
DRD4 P21917 1/20 0.36
MAPT P10636 4/20 0.35
THRB P10828 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
POLB P06746 2/20 0.33
NOS1 P29475 1/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
AR P10275 1/20 0.32
RXFP1 Q9HBX9 1/20 0.32
SLC6A3 Q01959 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20062956 0.76 ALDH1A1 (0.40) USP2ALOX15ALDH1A1GAANPC1
SCHEMBL2496995 0.67 NOS1 (0.38) USP2ALOX15ALDH1A1GAANPC1
SCHEMBL27533009 0.65 ALDH1A1 (0.34) USP2ALOX15ALDH1A1GAANPC1
SCHEMBL20071990 0.64 ROCK1 (0.42)
SCHEMBL20681890 0.64 HCRTR1 (0.35) ALDH1A1MAPTNPSR1POLB
SCHEMBL21652141 0.63 ALDH1A1 (0.48) USP2ALOX15ALDH1A1GAADRD4
SCHEMBL7068389 0.63 ALDH1A1 (0.35) USP2ALOX15ALDH1A1GAANPC1
SCHEMBL14196470 0.62 ALDH1A1 (0.41) ALDH1A1GAANPC1RAB9APKM
SCHEMBL1896492 0.62 KAT2B (0.65) ALOX15ALDH1A1GAANPC1RAB9A
SCHEMBL27850183 0.62 NPC1 (0.50) ALDH1A1GAANPC1RAB9APKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10541260-B2 Organic photoelectric conversion element, optical area sensor, imaging device, and imaging apparatus CANON KABUSHIKI KAISHA (JP) 2020-01-21 US disclosed
US-10193084-B2 2,2′-bibenzo[D]imidazolidene compound having heteromonocyclic groups at the 1-, 1′-, 3- and 3′- positions, and organic light-emitting element and display device containing the same CANON KABUSHIKI KAISHA (JP) 2019-01-29 US disclosed
US-20180108691-A1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, OPTICAL AREA SENSOR, IMAGING DEVICE, AND IMAGING APPARATUS CANON KABUSHIKI KAISHA (JP) 2018-04-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10193084-B2 2,2′-bibenzo[D]imidazolidene compound having heteromonocyclic groups at the 1-, 1′-, 3- and 3′- positions, and organic light-emitting element and display device containing the same BRD1, DRD1, NR2E3 USP2 3870/4885ALOX15 2947/4885ALDH1A1 395/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.