SCHEMBL20072003

SCHEMBL20072003

Cc1nc(N2c3ccc(C(C)(C)C)cc3N(c3nc(C)c(C)o3)C2C2N(c3nc(C)c(C)o3)c3ccc(C(C)(C)C)cc3N2c2nc(C)c(C)o2)oc1C

nearest known ligand 0.31

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
CSNK1D P48730 1/20 0.30
SCN10A Q9Y5Y9 2/20 0.30
TSHR P16473 1/20 0.30
HTT P42858 1/20 0.30
KCNH2 Q12809 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20062954 0.80 TRPV1 (0.31) TRPV1TSHRHTT
SCHEMBL20072095 0.74 HCRTR1 (0.42) MEN1KMT2ASCN10ATSHRHTT
SCHEMBL20681870 0.73 HCRTR1 (0.36) MEN1KMT2ACSNK1DSCN10ATSHR
SCHEMBL20071964 0.72 MAPT (0.31) TSHR
SCHEMBL20071768 0.71 SCN10A (0.33) MEN1KMT2ASCN10ATSHRKCNH2
SCHEMBL20681831 0.70 SCN10A (0.33) SCN10ATSHRKCNH2
SCHEMBL20681850 0.70 NR1H3 (0.33) SCN10AKCNH2
SCHEMBL20681894 0.69 ALDH1A1 (0.33) MEN1KMT2ASCN10AKCNH2
SCHEMBL18911705 0.68 MAPT (0.33) MEN1KMT2ACSNK1DTSHR
SCHEMBL20681889 0.68 KIF11 (0.43) SCN10ATSHRHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10541260-B2 Organic photoelectric conversion element, optical area sensor, imaging device, and imaging apparatus CANON KABUSHIKI KAISHA (JP) 2020-01-21 US disclosed
US-20180108691-A1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, OPTICAL AREA SENSOR, IMAGING DEVICE, AND IMAGING APPARATUS CANON KABUSHIKI KAISHA (JP) 2018-04-19 US disclosed