Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | PRKCH | P24723 | 1/20 | 0.37 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.37 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.37 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.35 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.35 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20072220 | 0.77 | ALDH1A1 (0.47) | ALDH1A1MAPTKDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL17577877 | 0.76 | ROCK1 (0.55) | ALDH1A1MAPTKDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL28163867 | 0.74 | ROCK1 (0.54) | ALDH1A1MAPTKDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL20072218 | 0.74 | ALDH1A1 (0.53) | ALDH1A1MAPTKDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL21559903 | 0.74 | ALDH1A1 (0.44) | ALDH1A1MAPTKDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL23841183 | 0.74 | KDM4E (0.44) | ALDH1A1MAPTKDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL8404559 | 0.72 | CYP1A2 (0.52) | ALDH1A1MAPTKDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL28866140 | 0.71 | PTGS1 (0.41) | MAPTPTGS1IMPDH2PTGS2 | |
| SCHEMBL14361044 | 0.71 | PTGS1 (0.37) | PTGS1PTGS2 | |
| SCHEMBL23841177 | 0.71 | ALDH1A1 (0.50) | ALDH1A1MAPTKDM4EKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3526239-B1 | HIF 1-ALPHA ANTISENSE OLIGONUCLEOTIDES | OLIPASS CORP (KR) | 2021-11-03 | — | — | EP | disclosed |
| WO-2018069764-A1 | HIF 1-ALPHA ANTISENSE OLIGONUCLEOTIDES | OLIPASS CORPORATION (KR) | 2018-04-19 | — | — | WO | disclosed |