SCHEMBL21559903

SCHEMBL21559903

Cc1cc(NC(C)S)c2ccncc2c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.44
MAPT P10636 5/20 0.44
KDM4E B2RXH2 4/20 0.44
KMT2A Q03164 5/20 0.43
LMNA P02545 2/20 0.41
SMN1; SMN2 Q16637 4/20 0.40
MEN1 O00255 2/20 0.39
LATS1 O95835 2/20 0.39
LATS2 Q9NRM7 1/20 0.39
NR3C1 P04150 1/20 0.37
HIPK2 Q9H2X6 2/20 0.36
TRPV1 Q8NER1 3/20 0.36
PRKCH P24723 2/20 0.36
PRKCE Q02156 2/20 0.36
PRKCQ Q04759 2/20 0.36
PRKCD Q05655 2/20 0.36
HTR2A P28223 1/20 0.36
HTR2C P28335 1/20 0.36
HTR2B P41595 1/20 0.36
CYP1A2 P05177 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20072222 0.74 ALDH1A1 (0.42) ALDH1A1MAPTKDM4EKMT2ASMN1; SMN2
SCHEMBL20072218 0.73 ALDH1A1 (0.53) ALDH1A1MAPTKDM4EKMT2ALMNA
SCHEMBL20072220 0.73 ALDH1A1 (0.47) ALDH1A1MAPTKDM4EKMT2ALMNA
SCHEMBL23841177 0.72 ALDH1A1 (0.50) ALDH1A1MAPTKDM4EKMT2ALMNA
SCHEMBL20990532 0.72 HASPIN (0.38) ALDH1A1MAPTKDM4ELMNASMN1; SMN2
SCHEMBL8404559 0.71 CYP1A2 (0.52) ALDH1A1MAPTKDM4EKMT2ALMNA
SCHEMBL801807 0.71 HIPK2 (0.45) LMNALATS1LATS2HIPK2TRPV1
SCHEMBL23841183 0.70 KDM4E (0.44) ALDH1A1MAPTKDM4EKMT2ALMNA
SCHEMBL11143217 0.68 LMNA (0.62) ALDH1A1MAPTKDM4EKMT2ALMNA
SCHEMBL19321774 0.66 CYP1A2 (0.46) ALDH1A1MAPTKDM4EKMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190345202-A1 ANDROGEN RECEPTOR ANTISENSE OLIGONUCLEOTIDES OLIPASS CORPORATION (KR) 2019-11-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190345202-A1 ANDROGEN RECEPTOR ANTISENSE OLIGONUCLEOTIDES AR, NR5A1, NR5A2 ALDH1A1 2699/4885MAPT 3013/4885KDM4E 4345/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.