SCHEMBL20072237

SCHEMBL20072237

CC(=O)OCCC1c2ccccc2-c2ccccc21

nearest known ligand 0.51

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.51
PPARG P37231 1/20 0.45
PPARA Q07869 1/20 0.45
KMT2A Q03164 2/20 0.42
ALDH1A1 P00352 1/20 0.42
FABP5 Q01469 3/20 0.41
FABP7 O15540 2/20 0.41
HTR2A P28223 1/20 0.41
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
EPHX2 P34913 1/20 0.40
SLC18A3 Q16572 1/20 0.39
CYP1A2 P05177 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5933473 0.84 PPARG (0.46) POLBPPARGPPARAKMT2AFABP5
SCHEMBL5932825 0.84 KMT2A (0.43) POLBPPARGPPARAKMT2AFABP5
SCHEMBL5933468 0.84 KMT2A (0.43) POLBPPARGPPARAKMT2AFABP5
SCHEMBL21553193 0.83 PPARG (0.46) POLBPPARGPPARAKMT2AFABP5
SCHEMBL5932833 0.83 PPARG (0.42) POLBPPARGPPARAKMT2AFABP5
SCHEMBL9328050 0.83 KMT2A (0.46) POLBPPARGPPARAKMT2AFABP5
SCHEMBL20072350 0.83 HTR2A (0.41) POLBPPARGPPARAKMT2AFABP5
SCHEMBL9328044 0.83 PPARG (0.42) POLBPPARGPPARAKMT2AFABP5
SCHEMBL4056199 0.83 PPARG (0.42) POLBPPARGPPARAKMT2AALDH1A1
SCHEMBL29608029 0.82 KMT2A (0.55) POLBKMT2AALDH1A1FABP5FABP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11319540-B2 HIF 1-alpha antisense oligonucleotides OLIPASS CORPORATION (KR) 2022-05-03 US disclosed
EP-3526239-B1 HIF 1-ALPHA ANTISENSE OLIGONUCLEOTIDES OLIPASS CORP (KR) 2021-11-03 EP disclosed
US-11162104-B2 SCN9A antisense pain killer OLIPASS CORPORATION (KR) 2021-11-02 US disclosed
US-20210292767-A1 HIF 1-ALPHA ANTISENSE OLIGONUCLEOTIDES OLIPASS CORPORATION (KR) 2021-09-23 US disclosed
US-20190345202-A1 ANDROGEN RECEPTOR ANTISENSE OLIGONUCLEOTIDES OLIPASS CORPORATION (KR) 2019-11-14 US disclosed
WO-2018069764-A1 HIF 1-ALPHA ANTISENSE OLIGONUCLEOTIDES OLIPASS CORPORATION (KR) 2018-04-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11319540-B2 HIF 1-alpha antisense oligonucleotides HIF1A, HIF1AN, UPF1 POLB 180/4885PPARG 1040/4885PPARA 800/4885
US-20190345202-A1 ANDROGEN RECEPTOR ANTISENSE OLIGONUCLEOTIDES AR, NR5A1, NR5A2 POLB 260/4885PPARG 206/4885PPARA 142/4885
US-20210292767-A1 HIF 1-ALPHA ANTISENSE OLIGONUCLEOTIDES HIF1A, HIF1AN, UPF1 POLB 180/4885PPARG 1040/4885PPARA 800/4885
US-11162104-B2 SCN9A antisense pain killer SCN9A, SCN7A, SCN8A POLB 2017/4885PPARG 4485/4885PPARA 3472/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.