⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8340404 | 0.74 | — | — | |
| SCHEMBL16589280 | 0.71 | ALDH1A1 (0.32) | — | |
| SCHEMBL20419625 | 0.70 | — | — | |
| SCHEMBL12410695 | 0.70 | APLNR (0.32) | — | |
| SCHEMBL13341568 | 0.70 | MAPT (0.33) | — | |
| SCHEMBL13341556 | 0.68 | PDE4A (0.33) | — | |
| SCHEMBL16474747 | 0.66 | ALDH1A1 (0.55) | — | |
| SCHEMBL8313126 | 0.64 | — | — | |
| SCHEMBL15331630 | 0.63 | PDE4A (0.31) | — | |
| SCHEMBL16684329 | 0.62 | CCR1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3526239-B1 | HIF 1-ALPHA ANTISENSE OLIGONUCLEOTIDES | OLIPASS CORP (KR) | 2021-11-03 | — | — | EP | disclosed |
| US-11162104-B2 | SCN9A antisense pain killer | OLIPASS CORPORATION (KR) | 2021-11-02 | — | — | US | disclosed |
| WO-2021057975-A1 | MUTANT IDH2 INHIBITOR AND APPLICATION THEREOF | 贝达药业股份有限公司 | 2021-04-01 | — | — | WO | disclosed |
| WO-2018069764-A1 | HIF 1-ALPHA ANTISENSE OLIGONUCLEOTIDES | OLIPASS CORPORATION (KR) | 2018-04-19 | — | — | WO | disclosed |