SCHEMBL20072307

SCHEMBL20072307

CNC(CCCN)C(=O)NC(Cc1ccccc1)C(N)=O

nearest known ligand 0.59

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
GNPAT O15228 1/20 0.52
CTSL P07711 1/20 0.52
FCER2 P06734 3/20 0.50
MMP1 P03956 2/20 0.50
NPFFR1 Q9GZQ6 1/20 0.49
NPFFR2 Q9Y5X5 1/20 0.49
GHSR Q92847 1/20 0.48
QRFPR Q96P65 1/20 0.48
FURIN P09958 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22845647 0.91 GHSR (0.55) GNPATCTSLGHSRFURIN
SCHEMBL18499711 0.91 GHSR (0.55) GNPATCTSLGHSRFURIN
SCHEMBL15499735 0.90 GNPAT (0.55) GNPATCTSLMMP1NPFFR1NPFFR2
SCHEMBL17550583 0.88 FCER2 (0.57) GNPATCTSLFCER2MMP1
SCHEMBL20159738 0.86 MMP2 (0.57) GNPATMMP1
SCHEMBL22695740 0.86 GNPAT (0.54) GNPATMMP1GHSRFURIN
SCHEMBL15948101 0.86 GNPAT (0.54) GNPATMMP1GHSRFURIN
SCHEMBL21788139 0.85 GNPAT (0.53) GNPATMMP1GHSR
SCHEMBL5703555 0.85 PRSS1 (0.59) CTSLFCER2
SCHEMBL14553984 0.85 GNPAT (0.48) GNPATCTSLMMP1NPFFR1NPFFR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3526239-B1 HIF 1-ALPHA ANTISENSE OLIGONUCLEOTIDES OLIPASS CORP (KR) 2021-11-03 EP disclosed
US-20190345202-A1 ANDROGEN RECEPTOR ANTISENSE OLIGONUCLEOTIDES OLIPASS CORPORATION (KR) 2019-11-14 US disclosed
WO-2018069764-A1 HIF 1-ALPHA ANTISENSE OLIGONUCLEOTIDES OLIPASS CORPORATION (KR) 2018-04-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190345202-A1 ANDROGEN RECEPTOR ANTISENSE OLIGONUCLEOTIDES AR, NR5A1, NR5A2 GNPAT 2278/4885CTSL 3909/4885FCER2 1664/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.