Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 9/20 | 0.46 |
| ▸ | NPY1R | P25929 | 6/20 | 0.46 |
| ▸ | Q9HBH1 | 1/20 | 0.41 | |
| ▸ | BIRC2 | Q13490 | 2/20 | 0.38 |
| ▸ | NPY2R | P49146 | 5/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 5/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21782578 | 0.95 | NPY4R (0.49) | NPY4RNPY1RNPY2RNPY5RHSD17B10 | |
| SCHEMBL17015152 | 0.85 | NPY4R (0.50) | NPY4RNPY1RPDFNPY2RNPY5R | |
| SCHEMBL19299731 | 0.85 | NPY4R (0.45) | NPY4RNPY1RNPY2RNPY5RDPP7 | |
| SCHEMBL27431216 | 0.84 | NPY4R (0.52) | NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL27431217 | 0.84 | NPY4R (0.52) | NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL27404766 | 0.84 | SIRT6 (0.45) | NPY4RNPY1RNPY2RNPY5RSIRT6 | |
| SCHEMBL30434218 | 0.82 | NPY4R (0.59) | NPY4RNPY1RNPY2RNPY5RDPP7 | |
| SCHEMBL16263594 | 0.82 | NPY4R (0.49) | NPY4RNPY1RPDFNPY2RNPY5R | |
| SCHEMBL27335222 | 0.81 | NPY4R (0.48) | NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL27335224 | 0.81 | NPY4R (0.48) | NPY4RNPY1RNPY2RNPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018071033-A1 | COACERVATE HYALURONAN HYDROGELS FOR DERMAL FILLER APPLICATIONS | ALLERGAN, INC. (US) | 2018-04-19 | — | — | WO | disclosed |