Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 15/20 | 0.50 |
| ▸ | NPY1R | P25929 | 9/20 | 0.50 |
| ▸ | NPY5R | Q15761 | 8/20 | 0.41 |
| ▸ | NPY2R | P49146 | 5/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | Q9HBH1 | 1/20 | 0.35 | |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21782578 | 0.90 | NPY4R (0.49) | NPY4RNPY1RNPY5RNPY2RFOLH1 | |
| SCHEMBL27431216 | 0.90 | NPY4R (0.52) | NPY4RNPY1RNPY5RNPY2RFOLH1 | |
| SCHEMBL27431217 | 0.90 | NPY4R (0.52) | NPY4RNPY1RNPY5RNPY2RFOLH1 | |
| SCHEMBL23836846 | 0.89 | NPY4R (0.42) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL16263594 | 0.87 | NPY4R (0.49) | NPY4RNPY1RNPY5RNPY2RFOLH1 | |
| SCHEMBL30434218 | 0.87 | NPY4R (0.59) | NPY4RNPY1RNPY5RNPY2R | |
| Hydrochloric Acid SCHEMBL29508688 | 0.86 | NPY4R (0.58) | NPY4RNPY1RNPY5RNPY2R | |
| Hydrochloric Acid SCHEMBL29726986 | 0.86 | NPY4R (0.58) | NPY4RNPY1RNPY5RNPY2R | |
| Hydrochloric Acid SCHEMBL30380134 | 0.86 | NPY4R (0.58) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL20072813 | 0.85 | NPY4R (0.46) | NPY4RNPY1RNPY5RNPY2RPDF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170247324-A1 | ALDEHYDE CAPTURE LIGATION TECHNOLOGY FOR SYNTHESIS OF AMIDE BONDS | UNIV NEW YORK (US) | 2017-08-31 | — | — | US | disclosed |
| US-9593142-B2 | Aldehyde capture ligation technology for synthesis of amide bonds | NEW YORK UNIVERSITY (US) | 2017-03-14 | — | — | US | disclosed |
| US-20170029381-A1 | TETRAHYDRO-BENZOIMIDAZOLYL MODULATORS OF TGR5 | JANSSEN PHARMACEUTICA NV (BE) | 2017-02-02 | — | — | US | disclosed |
| US-20150232504-A1 | ALDEHYDE CAPTURE LIGATION TECHNOLOGY FOR SYNTHESIS OF AMIDE BONDS | NEW YORK UNIVERSITY (US) | 2015-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170247324-A1 | ALDEHYDE CAPTURE LIGATION TECHNOLOGY FOR SYNTHESIS OF AMIDE BONDS | ALDH3A1, ALDH2, ALDH1A1 | NPY4R 2737/4885NPY1R 3496/4885NPY5R 3191/4885 |
| US-20170029381-A1 | TETRAHYDRO-BENZOIMIDAZOLYL MODULATORS OF TGR5 | GLRA1, GRM5, TRHR | NPY4R 34/4885NPY1R 21/4885NPY5R 4/4885 |
| US-20150232504-A1 | ALDEHYDE CAPTURE LIGATION TECHNOLOGY FOR SYNTHESIS OF AMIDE BONDS | ALDH3A1, ALDH2, ALDH1A1 | NPY4R 2737/4885NPY1R 3496/4885NPY5R 3191/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.