Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 11/20 | 0.60 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.54 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.50 |
| ▸ | GLP1R | P43220 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16666081 | 0.88 | FOLH1 (0.61) | FOLH1NAALAD2RIMKLANOD1GLP1R | |
| SCHEMBL23252356 | 0.87 | FOLH1 (0.67) | FOLH1NAALAD2RIMKLAEPHX2NOD1 | |
| SCHEMBL18058887 | 0.87 | FOLH1 (0.67) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL21164584 | 0.87 | FOLH1 (0.56) | FOLH1NAALAD2RIMKLANOD1 | |
| SCHEMBL19155799 | 0.86 | FOLH1 (0.56) | FOLH1NAALAD2RIMKLAEPHX2NOD1 | |
| SCHEMBL13946267 | 0.86 | FOLH1 (0.72) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL16122936 | 0.85 | FOLH1 (0.60) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL20018409 | 0.85 | FOLH1 (0.64) | FOLH1NAALAD2RIMKLANOD1GLP1R | |
| SCHEMBL16374702 | 0.85 | FOLH1 (0.64) | FOLH1NAALAD2RIMKLANOD1GLP1R | |
| SCHEMBL18412144 | 0.85 | FOLH1 (0.64) | FOLH1NAALAD2RIMKLAGLP1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220396621-A1 | TARGETING AGENT ANTIBODY CONJUGATES AND USES THEREOF | SCRIPPS RESEARCH INST (US) | 2022-12-15 | — | — | US | disclosed |
| US-11377496-B2 | Targeting agent antibody conjugates and uses thereof | THE SCRIPPS RESEARCH INSTITUTE (US) | 2022-07-05 | — | — | US | disclosed |
| US-20190315863-A1 | TARGETING AGENT ANTIBODY CONJUGATES AND USES THEREOF | THE SCRIPPS RESEARCH INSTITUTE | 2019-10-17 | — | — | US | disclosed |
| US-20180104354-A1 | CHIMERIC ANTIGEN RECEPTOR T CELL SWITCHES AND USES THEREOF | THE SCRIPPS RESEARCH INSTITUTE | 2018-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180104354-A1 | CHIMERIC ANTIGEN RECEPTOR T CELL SWITCHES AND USES THEREOF | ICOS, HAVCR2, CD2 | FOLH1 1953/4885NAALAD2 487/4885RIMKLA 3128/4885 |
| US-20220396621-A1 | TARGETING AGENT ANTIBODY CONJUGATES AND USES THEREOF | CD22, FCGR2A, CD47 | FOLH1 226/4885NAALAD2 404/4885RIMKLA 1357/4885 |
| US-20190315863-A1 | TARGETING AGENT ANTIBODY CONJUGATES AND USES THEREOF | FCGR2A, CD22, FCGR3B | FOLH1 340/4885NAALAD2 437/4885RIMKLA 1385/4885 |
| US-11377496-B2 | Targeting agent antibody conjugates and uses thereof | FCGR2A, CD22, FCGR3B | FOLH1 340/4885NAALAD2 437/4885RIMKLA 1385/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.