SCHEMBL20074050

SCHEMBL20074050

COc1ccc2c(c1)sc1cc3c(cc1n2C)sc1cc(OC)ccc1n3C

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.70
SMN1; SMN2 Q16637 5/20 0.70
ALDH1A1 P00352 4/20 0.70
KDM4E B2RXH2 3/20 0.50
HPGD P15428 2/20 0.50
HSD17B10 Q99714 2/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
PARP15 Q460N3 2/20 0.50
PARP10 Q53GL7 2/20 0.50
TNKS2 Q9H2K2 2/20 0.50
PARP2 Q9UGN5 2/20 0.50
MEN1 O00255 1/20 0.50
HTT P42858 1/20 0.50
KMT2A Q03164 1/20 0.50
BCHE P06276 1/20 0.44
ACHE P22303 1/20 0.44
RAB9A P51151 2/20 0.43
LMNA P02545 2/20 0.43
TSHR P16473 2/20 0.43
TP53 P04637 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6340728 0.82 ALDH1A1 (0.66) MAPTSMN1; SMN2ALDH1A1KDM4EHPGD
SCHEMBL4813428 0.82 MAPT (1.00) MAPTSMN1; SMN2ALDH1A1KDM4EHPGD
SCHEMBL11781952 0.82 ALDH1A1 (0.66) MAPTSMN1; SMN2ALDH1A1KDM4EHPGD
SCHEMBL20065671 0.78 ALDH1A1 (0.65) MAPTSMN1; SMN2ALDH1A1KDM4EHPGD
SCHEMBL22349312 0.77 ALDH1A1 (0.48) MAPTSMN1; SMN2ALDH1A1KDM4EHPGD
SCHEMBL11047658 0.74 ALDH1A1 (0.81) MAPTSMN1; SMN2ALDH1A1KDM4EHPGD
SCHEMBL20091112 0.73 MAPT (0.57) MAPTSMN1; SMN2ALDH1A1KDM4EHPGD
SCHEMBL20065654 0.72 F12 (0.59) MAPTSMN1; SMN2ALDH1A1KDM4EL3MBTL1
SCHEMBL30784640 0.72 F12 (0.59) MAPTSMN1; SMN2ALDH1A1KDM4EL3MBTL1
SCHEMBL4614424 0.71 SMN1; SMN2 (0.49) MAPTSMN1; SMN2ALDH1A1KDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3526204-B1 NEAR-IR ABSORPTIVE COMPOUNDS AND DEVICES INCORPORATING THE SAME GENTEX CORP (US) 2021-02-17 EP disclosed
US-20180105738-A1 NEAR-IR ABSORPTIVE COMPOUNDS AND DEVICES INCORPORATING THE SAME GENTEX CORP (US) 2018-04-19 US disclosed