Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 1.00 |
| ▸ | F12 | P00748 | 1/20 | 0.53 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.48 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.48 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.48 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20074050 | 0.82 | MAPT (0.70) | MAPTSMN1; SMN2ALDH1A1PARP15PARP10 | |
| SCHEMBL6251438 | 0.81 | SMN1; SMN2 (0.68) | MAPTSMN1; SMN2ALDH1A1F12HSD17B10 | |
| SCHEMBL11781952 | 0.79 | ALDH1A1 (0.66) | MAPTSMN1; SMN2ALDH1A1PARP15PARP10 | |
| SCHEMBL6340728 | 0.79 | ALDH1A1 (0.66) | MAPTSMN1; SMN2ALDH1A1PARP15PARP10 | |
| SCHEMBL11373828 | 0.79 | MAPT (0.65) | MAPTSMN1; SMN2ALDH1A1PARP15PARP10 | |
| SCHEMBL20065671 | 0.79 | ALDH1A1 (0.65) | MAPTSMN1; SMN2ALDH1A1PARP15PARP10 | |
| SCHEMBL11273812 | 0.75 | MAPT (0.60) | MAPTSMN1; SMN2ALDH1A1F12PARP15 | |
| Bromide SCHEMBL10464587 | 0.73 | ALDH1A1 (0.57) | MAPTSMN1; SMN2ALDH1A1PARP15PARP10 | |
| SCHEMBL20091112 | 0.73 | MAPT (0.57) | MAPTSMN1; SMN2ALDH1A1PARP15PARP10 | |
| SCHEMBL14080064 | 0.70 | MAPT (0.52) | MAPTSMN1; SMN2ALDH1A1PARP15PARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7413578-B2 | Symmetric and assymetric dyes with a mesomeric structure, e.g., 2-[(1-ethyl-4(1H)-quinolinylidene)amino]-6-methoxy-3-methyl-1,3-benzothiazol-3-ium tetrafluoroborate; may be used to dye predamaged sections of hair without oxidizing agent neat or mixed with an acidic, neutral or basic aqueous diluent | THE PROCTER & GAMBLE COMPANY (US) | 2008-08-19 | — | — | US | disclosed |
| EP-1844108-A2 | COLORANTS COMPRISING CATIONIC AZACYANINE DYES | Wella Aktiengesellschaft (DE) | 2007-10-17 | — | — | EP | disclosed |
| US-20070000071-A1 | Colorants comprising cationic azacyanine dyes | PROCTER & GAMBLE COMPANY, THE | 2007-01-04 | — | — | US | disclosed |
| WO-2006081244-A2 | COLORANTS COMPRISING CATIONIC AZACYANINE DYES | THE PROCTER & GAMBLE COMPANY (US) | 2006-08-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070000071-A1 | Colorants comprising cationic azacyanine dyes | KRT18, IK, NUP205 | MAPT 2811/4885SMN1; SMN2 2854/4885ALDH1A1 1520/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.