SCHEMBL20074705

SCHEMBL20074705

CC(=N)/C=C(/C)Nc1cc(Nc2n[nH]c(-c3ccc(F)cc3F)c2Cl)ncn1

nearest known ligand 0.61

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SLC34A1 Q06495 20/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20074704 0.76 SLC34A1 (1.00) SLC34A1
SCHEMBL20074991 0.64 SLC34A1 (1.00) SLC34A1
SCHEMBL20075348 0.59 SLC34A1 (0.70) SLC34A1
SCHEMBL20075560 0.58 SLC34A1 (1.00) SLC34A1
SCHEMBL20075266 0.57 SLC34A1 (0.61) SLC34A1
SCHEMBL20075042 0.57 SLC34A1 (0.71) SLC34A1
SCHEMBL19392163 0.57 MAPT (0.45)
SCHEMBL20074781 0.57 SLC34A1 (0.66) SLC34A1
SCHEMBL28805913 0.55 ALPL (0.36) SLC34A1
SCHEMBL6726783 0.55 KMO (0.58) SLC34A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3526212-B1 SUBSTITUTED 6-(1H-PYRAZOL-1-YL)PYRIMIDIN-4-AMINE DERIVATIVES AND USES THEREOF BAYER AG (DE) 2021-12-22 EP disclosed
WO-2018069222-A1 SUBSTITUTED 6-(1H-PYRAZOL-1-YL)PYRIMIDIN-4-AMINE DERIVATIVES AND USES THEREOF BAYER AKTIENGESELLSCHAFT (DE) 2018-04-19 WO disclosed