Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC34A1 | Q06495 | 18/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24114841 | 0.86 | SLC34A1 (0.42) | SLC34A1AR | |
| SCHEMBL20075346 | 0.85 | SLC34A1 (0.54) | SLC34A1AR | |
| SCHEMBL20075131 | 0.83 | SLC34A1 (0.56) | SLC34A1AR | |
| SCHEMBL20075631 | 0.82 | SLC34A1 (0.56) | SLC34A1AR | |
| SCHEMBL20075367 | 0.80 | SLC34A1 (0.58) | SLC34A1AR | |
| SCHEMBL20075745 | 0.79 | SLC34A1 (0.44) | SLC34A1 | |
| SCHEMBL24114826 | 0.78 | PDE4D (0.51) | SLC34A1 | |
| SCHEMBL20074889 | 0.74 | SLC34A1 (0.53) | SLC34A1 | |
| SCHEMBL20075530 | 0.73 | SLC34A1 (0.55) | SLC34A1 | |
| SCHEMBL378335 | 0.71 | SLC34A1 (0.57) | SLC34A1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3526212-B1 | SUBSTITUTED 6-(1H-PYRAZOL-1-YL)PYRIMIDIN-4-AMINE DERIVATIVES AND USES THEREOF | BAYER AG (DE) | 2021-12-22 | — | — | EP | disclosed |
| WO-2018069222-A1 | SUBSTITUTED 6-(1H-PYRAZOL-1-YL)PYRIMIDIN-4-AMINE DERIVATIVES AND USES THEREOF | BAYER AKTIENGESELLSCHAFT (DE) | 2018-04-19 | — | — | WO | disclosed |