SCHEMBL24114841

SCHEMBL24114841

Cc1nn(-c2cc(N)[nH]c3c(C)n(-c4ccc(C#N)cc4)nc3ccn2)c(C)c1C

nearest known ligand 0.42

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SLC34A1 Q06495 18/20 0.42
AR P10275 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20075346 0.90 SLC34A1 (0.54) SLC34A1AR
SCHEMBL20075131 0.87 SLC34A1 (0.56) SLC34A1AR
SCHEMBL20075631 0.87 SLC34A1 (0.56) SLC34A1AR
SCHEMBL20074888 0.86 SLC34A1 (0.52) SLC34A1AR
SCHEMBL20075367 0.84 SLC34A1 (0.58) SLC34A1AR
SCHEMBL24114826 0.84 PDE4D (0.51) SLC34A1
SCHEMBL20075745 0.82 SLC34A1 (0.44) SLC34A1
SCHEMBL20075166 0.73 SLC34A1 (0.45) SLC34A1AR
SCHEMBL20037190 0.69 SMN1; SMN2 (0.62) SLC34A1AR
SCHEMBL20075295 0.69 SLC34A1 (0.52) SLC34A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3526212-B1 SUBSTITUTED 6-(1H-PYRAZOL-1-YL)PYRIMIDIN-4-AMINE DERIVATIVES AND USES THEREOF BAYER AG (DE) 2021-12-22 EP disclosed