Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC34A1 | Q06495 | 13/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24114826 | 0.94 | PDE4D (0.51) | SLC34A1PDE4DP2RY12 | |
| SCHEMBL20075131 | 0.88 | SLC34A1 (0.56) | SLC34A1PDE4D | |
| SCHEMBL20075346 | 0.82 | SLC34A1 (0.54) | SLC34A1 | |
| SCHEMBL24114841 | 0.82 | SLC34A1 (0.42) | SLC34A1 | |
| SCHEMBL20075631 | 0.80 | SLC34A1 (0.56) | SLC34A1 | |
| SCHEMBL20074888 | 0.79 | SLC34A1 (0.52) | SLC34A1 | |
| SCHEMBL20075367 | 0.77 | SLC34A1 (0.58) | SLC34A1 | |
| SCHEMBL20075744 | 0.76 | SLC34A1 (0.76) | SLC34A1 | |
| SCHEMBL24114890 | 0.73 | SLC34A1 (0.61) | SLC34A1 | |
| SCHEMBL20075582 | 0.73 | SLC34A1 (0.59) | SLC34A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018069222-A1 | SUBSTITUTED 6-(1H-PYRAZOL-1-YL)PYRIMIDIN-4-AMINE DERIVATIVES AND USES THEREOF | BAYER AKTIENGESELLSCHAFT (DE) | 2018-04-19 | — | — | WO | disclosed |