Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25636605 | 0.82 | ALDH1A1 (0.36) | ALDH1A1MAPK1TSHR | |
| SCHEMBL20372670 | 0.81 | ALDH1A1 (0.32) | ALDH1A1TSHR | |
| SCHEMBL18591727 | 0.81 | — | — | |
| SCHEMBL25053665 | 0.80 | — | — | |
| SCHEMBL974387 | 0.79 | ALDH1A1 (0.37) | ALDH1A1MAPK1TSHRCYP2C19 | |
| SCHEMBL14306653 | 0.79 | CA2 (0.37) | ALDH1A1MAPK1TSHR | |
| SCHEMBL20075973 | 0.79 | MAPK1 (0.36) | ALDH1A1MAPK1TSHRCYP2C19 | |
| SCHEMBL19606414 | 0.77 | — | — | |
| SCHEMBL29326769 | 0.77 | — | — | |
| SCHEMBL10245201 | 0.75 | ALDH1A1 (0.41) | ALDH1A1MAPK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018071606-A1 | COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF ANDROGEN RECEPTOR | Arvinas, Inc. (US) | 2018-04-19 | — | — | WO | disclosed |