Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G1B | P04054 | 1/20 | 0.50 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.50 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 13/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15384677 | 1.00 | PLA2G1B (0.50) | PLA2G1BPLA2G2ADNM1KCNH2TSHR | |
| SCHEMBL23846697 | 1.00 | PLA2G1B (0.50) | PLA2G1BPLA2G2ADNM1KCNH2TSHR | |
| SCHEMBL15186998 | 0.98 | PLA2G1B (0.47) | PLA2G1BPLA2G2ADNM1KCNH2 | |
| SCHEMBL9807746 | 0.91 | DNM1 (0.52) | PLA2G1BPLA2G2ADNM1KCNH2TSHR | |
| SCHEMBL10411256 | 0.91 | DNM1 (0.52) | PLA2G1BPLA2G2ADNM1KCNH2TSHR | |
| SCHEMBL17526607 | 0.91 | DNM1 (0.52) | PLA2G1BPLA2G2ADNM1KCNH2TSHR | |
| SCHEMBL19333372 | 0.91 | DNM1 (0.52) | PLA2G1BPLA2G2ADNM1KCNH2TSHR | |
| SCHEMBL9807760 | 0.91 | DNM1 (0.52) | PLA2G1BPLA2G2ADNM1KCNH2TSHR | |
| SCHEMBL10712988 | 0.91 | DNM1 (0.52) | PLA2G1BPLA2G2ADNM1KCNH2TSHR | |
| SCHEMBL10712630 | 0.91 | DNM1 (0.52) | PLA2G1BPLA2G2ADNM1KCNH2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10647747-B2 | Cyclosporin derivatives and uses thereof | S&T GLOBAL INC. (US) | 2020-05-12 | — | — | US | disclosed |
| US-20180105558-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | S&T GLOBAL INC. | 2018-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10647747-B2 | Cyclosporin derivatives and uses thereof | FKBP5, FKBP1B, MALT1 | PLA2G1B 4676/4885PLA2G2A 4850/4885DNM1 3114/4885 |
| US-20180105558-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | FKBP1B, MALT1, FKBP5 | PLA2G1B 4667/4885PLA2G2A 4836/4885DNM1 3016/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.