SCHEMBL20076418

SCHEMBL20076418

C=C(C)C1C(c2cc(Cl)c(Br)c(Cl)c2)C1(Cl)Cl

nearest known ligand 0.31

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.30
LMNA P02545 1/20 0.30
MAPT P10636 1/20 0.30
MAPK1 P28482 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21021894 0.83 MEN1 (0.31) MEN1LMNAMAPTMAPK1KMT2A
SCHEMBL21021898 0.81 SLC9A1 (0.35) MEN1LMNAMAPTMAPK1KMT2A
SCHEMBL21021384 0.80 SLC9A1 (0.33) MEN1LMNAMAPTMAPK1KMT2A
SCHEMBL20076411 0.79 NOTUM (0.31)
SCHEMBL21021470 0.78 CYP3A4 (0.36) MEN1LMNAMAPTMAPK1KMT2A
SCHEMBL18143628 0.78 ALDH1A1 (0.36) MEN1LMNAMAPTMAPK1KMT2A
SCHEMBL18143627 0.78 ALDH1A1 (0.36) MEN1LMNAMAPTMAPK1KMT2A
SCHEMBL18143626 0.78 ALDH1A1 (0.36) MEN1LMNAMAPTMAPK1KMT2A
SCHEMBL21021293 0.77 MEN1 (0.35) MEN1LMNAMAPTMAPK1KMT2A
SCHEMBL21021820 0.76 SLC6A2 (0.35) MEN1LMNAMAPTMAPK1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018071327-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO DOW AGROSCIENCES LLC (US) 2018-04-19 WO disclosed