SCHEMBL20076436

SCHEMBL20076436

C=C(Nc1ccc(Cl)c(C)c1)C1C(c2cc(C)cc(Cl)c2)C1(C)C

nearest known ligand 0.36

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SLC9A1 P19634 2/20 0.36
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
ALDH1A1 P00352 2/20 0.33
LMNA P02545 1/20 0.33
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33
NPC1 O15118 1/20 0.33
RECQL P46063 1/20 0.31
BLM P54132 1/20 0.30
RAPGEF4 Q8WZA2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21022180 0.87 NPC1 (0.33) MEN1KMT2AALDH1A1LMNAGAA
SCHEMBL21021127 0.86 SLC9A1 (0.33) SLC9A1MEN1KMT2AALDH1A1LMNA
SCHEMBL21022006 0.82 MEN1 (0.39) SLC9A1MEN1KMT2AALDH1A1LMNA
SCHEMBL20076548 0.81 POLB (0.34) SLC9A1MEN1KMT2AALDH1A1GAA
SCHEMBL21021635 0.81 SLC9A1 (0.30) SLC9A1NPC1
SCHEMBL21020721 0.80 SLC9A1 (0.36) SLC9A1MEN1KMT2AALDH1A1LMNA
SCHEMBL20076742 0.80 MEN1 (0.31) MEN1KMT2AALDH1A1LMNAGAA
SCHEMBL21021054 0.79
SCHEMBL21021736 0.79 KMT2A (0.38) MEN1KMT2AALDH1A1LMNAGAA
SCHEMBL21021734 0.78 MEN1 (0.43) SLC9A1MEN1KMT2AALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3283459-B1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO DOW AGROSCIENCES LLC (US) 2019-05-22 EP disclosed
WO-2018071327-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO DOW AGROSCIENCES LLC (US) 2018-04-19 WO disclosed