Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 5/20 | 0.62 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.62 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.62 |
| ▸ | NFE2L2 | Q16236 | 6/20 | 0.50 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | GPR183 | P32249 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20076672 | 0.84 | PTGS1 (0.69) | PTGS1PTGS2ALOX5NFE2L2TUBB1 | |
| SCHEMBL21021173 | 0.81 | CHAT (0.47) | PTGS1PTGS2ALOX5NFE2L2TUBB1 | |
| SCHEMBL27432274 | 0.80 | RARB (0.43) | PTGS1PTGS2ALOX5NFE2L2TUBB1 | |
| SCHEMBL6953517 | 0.78 | SLC6A2 (0.45) | PTGS1PTGS2ALOX5GABRA1SIGMAR1 | |
| SCHEMBL21022141 | 0.78 | ALOX5 (0.45) | PTGS1PTGS2ALOX5NFE2L2TUBB1 | |
| SCHEMBL6546261 | 0.78 | ALOX5 (0.63) | PTGS1PTGS2ALOX5TUBB1LMNA | |
| SCHEMBL16853122 | 0.78 | ALOX5 (0.63) | PTGS1PTGS2ALOX5TUBB1LMNA | |
| SCHEMBL9026437 | 0.78 | ALOX5 (0.63) | PTGS1PTGS2ALOX5TUBB1LMNA | |
| SCHEMBL9026432 | 0.78 | ALOX5 (0.63) | PTGS1PTGS2ALOX5TUBB1LMNA | |
| SCHEMBL21021697 | 0.77 | ALOX5 (0.47) | PTGS1PTGS2ALOX5NFE2L2TUBB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018071327-A1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2018-04-19 | — | — | WO | disclosed |