Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 14/20 | 0.42 |
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.34 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21021699 | 0.87 | ALOX5 (0.45) | ALOX5PTGS1PTGS2TUBB1NFE2L2 | |
| SCHEMBL16955721 | 0.83 | TRPA1 (0.38) | ALOX5PTGS1PTGS2RAB9A | |
| SCHEMBL21021705 | 0.81 | ALOX5 (0.45) | ALOX5PTGS1PTGS2TUBB1NFE2L2 | |
| SCHEMBL20076447 | 0.78 | PTGS1 (0.62) | ALOX5PTGS1PTGS2TUBB1NFE2L2 | |
| SCHEMBL21021708 | 0.77 | ALOX5 (0.45) | ALOX5PTGS1PTGS2TUBB1DHFR | |
| SCHEMBL21021173 | 0.77 | CHAT (0.47) | ALOX5PTGS1PTGS2TUBB1NFE2L2 | |
| SCHEMBL21021781 | 0.75 | PTGS1 (0.50) | ALOX5PTGS1PTGS2TUBB1NFE2L2 | |
| SCHEMBL23384496 | 0.75 | NFE2L2 (0.66) | ALOX5PTGS1PTGS2TUBB1NFE2L2 | |
| SCHEMBL25034503 | 0.75 | NFE2L2 (0.51) | NFE2L2RELA | |
| SCHEMBL6546261 | 0.74 | ALOX5 (0.63) | ALOX5PTGS1PTGS2TUBB1DHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3283459-B1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2019-05-22 | — | — | EP | disclosed |