Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21021658 | 0.79 | ALDH1A1 (0.43) | ALDH1A1RECQLHSD17B10CYP3A4GSTO1 | |
| SCHEMBL1799567 | 0.77 | CYP3A4 (0.53) | ALDH1A1POLBKDM4EHPGDCASP1 | |
| Hydrochloric Acid SCHEMBL3399071 | 0.75 | CYP3A4 (0.52) | ALDH1A1POLBKDM4EHPGDCASP1 | |
| SCHEMBL20076588 | 0.75 | MAPT (0.39) | ALDH1A1KDM4EHPGDCASP1CASP7 | |
| SCHEMBL1800169 | 0.73 | ALDH1A1 (0.46) | ALDH1A1POLBKDM4EHPGDCASP1 | |
| SCHEMBL3789837 | 0.73 | ALDH1A1 (0.46) | ALDH1A1POLBKDM4EHPGDCASP1 | |
| SCHEMBL320706 | 0.72 | ALDH1A1 (0.43) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL3395942 | 0.72 | POLB (0.45) | ALDH1A1POLBKDM4EHPGDCASP1 | |
| SCHEMBL3398743 | 0.72 | ABL1 (0.65) | ALDH1A1POLBKDM4EHPGDCASP1 | |
| SCHEMBL3397984 | 0.72 | RAPGEF4 (0.50) | ALDH1A1POLBKDM4EHPGDCASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018071327-A1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2018-04-19 | — | — | WO | disclosed |