SCHEMBL20076575

SCHEMBL20076575

C=C(Nc1cc(C)c(Cl)c(C)c1)C1CC1(C)Cl

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
CYP3A4 P08684 1/20 0.33
CHRM1 P11229 1/20 0.33
ALOX15 P16050 1/20 0.33
MAOA P21397 1/20 0.33
TBXA2R P21731 1/20 0.33
ADRA1A P35348 1/20 0.33
HTR2B P41595 1/20 0.33
DRD1 P21728 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20076414 0.84 ALDH1A1 (0.39) ALDH1A1L3MBTL1
SCHEMBL20076545 0.77 CNR1 (0.33) ALDH1A1L3MBTL1
SCHEMBL20076450 0.75 ALDH1A1 (0.37) ALDH1A1L3MBTL1
SCHEMBL20076718 0.73 ALDH1A1 (0.45) ALDH1A1L3MBTL1
SCHEMBL20076562 0.73 MEN1 (0.35)
SCHEMBL21021640 0.72 RAB9A (0.34) ALDH1A1L3MBTL1CYP3A4
SCHEMBL21021233 0.71 RAB9A (0.36) ALDH1A1L3MBTL1CYP3A4
SCHEMBL20076602 0.71 ALDH1A1 (0.36) ALDH1A1L3MBTL1
SCHEMBL20076953 0.70 NPC1 (0.32) ALDH1A1L3MBTL1
SCHEMBL20076616 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018071327-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO DOW AGROSCIENCES LLC (US) 2018-04-19 WO disclosed