Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TMPRSS4 | Q9NRS4 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20076572 | 0.77 | IDH1 (0.40) | SMN1; SMN2RAB9AMAPTLMNATSHR | |
| SCHEMBL20076738 | 0.71 | DHODH (0.32) | SMN1; SMN2RAB9AMAPTLMNATP53 | |
| SCHEMBL21020826 | 0.68 | MEN1 (0.43) | SMN1; SMN2RAB9ALMNATSHRHSD17B10 | |
| SCHEMBL18160308 | 0.67 | F10 (0.55) | SMN1; SMN2RAB9ALMNANPC1KMT2A | |
| SCHEMBL13848099 | 0.67 | ALDH1A1 (0.46) | SMN1; SMN2RAB9AMAPTLMNATSHR | |
| SCHEMBL4599083 | 0.66 | SMN1; SMN2 (0.49) | SMN1; SMN2HSD17B10KMT2AMEN1ABCB1 | |
| SCHEMBL21021070 | 0.66 | HDAC1 (0.59) | SMN1; SMN2RAB9AMAPTLMNAHSD17B10 | |
| SCHEMBL14363357 | 0.66 | TMPRSS4 (0.74) | TSHRKMT2ATMPRSS4MEN1P2RX1 | |
| SCHEMBL3421898 | 0.66 | SMN1; SMN2 (0.51) | SMN1; SMN2RAB9ALMNATSHRHSD17B10 | |
| SCHEMBL18160239 | 0.65 | TAS1R3 (0.58) | SMN1; SMN2RAB9AMAPTLMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018071327-A1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2018-04-19 | — | — | WO | disclosed |