Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | CFTR | P13569 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15914665 | 0.80 | TSHR (0.50) | TSHRGLAPOLBGAAKDM4E | |
| SCHEMBL24973071 | 0.79 | CES2 (0.39) | MEN1KMT2AKIF11PDE3BPDE3A | |
| SCHEMBL38659817 | 0.78 | GAA (0.52) | TSHRGLAPOLBGAAKDM4E | |
| SCHEMBL20076491 | 0.77 | KDM4E (0.37) | TSHRKDM4EMEN1KMT2ATDP1 | |
| SCHEMBL20076895 | 0.76 | KDM4E (0.39) | TSHRKDM4EMEN1KMT2ATDP1 | |
| SCHEMBL12816383 | 0.74 | TSHR (0.45) | TSHRGLAPOLBGAAKDM4E | |
| SCHEMBL24118132 | 0.74 | TSHR (0.45) | TSHRGLAPOLBGAAKDM4E | |
| SCHEMBL20076656 | 0.73 | THRB (0.41) | TSHRKDM4EMEN1KMT2ATDP1 | |
| SCHEMBL25810982 | 0.72 | TSHR (0.43) | TSHRGLAPOLBGAAKDM4E | |
| SCHEMBL30688815 | 0.71 | GAA (0.42) | TSHRGLAPOLBGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018071327-A1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2018-04-19 | — | — | WO | disclosed |