Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | RHOA | P61586 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | CCKBR | P32239 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.31 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.31 |
| ▸ | TGM2 | P21980 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21021582 | 0.75 | MEN1 (0.33) | MEN1KMT2AALDH1A1EPHX2 | |
| SCHEMBL21021630 | 0.71 | MEN1 (0.37) | MEN1KMT2APOLBTDP1TP53 | |
| SCHEMBL20076545 | 0.70 | CNR1 (0.33) | MEN1KMT2AALDH1A1 | |
| SCHEMBL5950789 | 0.70 | ALDH1A1 (0.58) | MEN1KMT2APOLBTP53ALDH1A1 | |
| SCHEMBL27823783 | 0.70 | TDP1 (0.64) | MEN1KMT2APOLBTDP1TP53 | |
| SCHEMBL21022193 | 0.69 | ALDH1A1 (0.34) | POLBALDH1A1EPHX2 | |
| SCHEMBL4336194 | 0.68 | MEN1 (0.51) | MEN1KMT2APOLBTDP1TP53 | |
| SCHEMBL20076826 | 0.68 | HTR1F (0.36) | MEN1KMT2ATP53ALDH1A1EPHX2 | |
| SCHEMBL7048754 | 0.67 | TP53 (0.54) | MEN1KMT2APOLBTDP1TP53 | |
| SCHEMBL11335933 | 0.67 | SMN1; SMN2 (0.56) | MEN1KMT2APOLBTP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018071327-A1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2018-04-19 | — | — | WO | disclosed |