SCHEMBL20076798

SCHEMBL20076798

C=C(Nc1cc(F)c(C)c(CC(C)(F)F)c1)C1C(c2ccc(F)c(C)c2)C1(C)C

nearest known ligand 0.41

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SLC9A1 P19634 3/20 0.41
HTR2A P28223 1/20 0.30
HTR2C P28335 1/20 0.30
HTR2B P41595 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20076803 0.82 SLC9A1 (0.32) SLC9A1
SCHEMBL20076729 0.73 SLC9A1 (0.44) SLC9A1
SCHEMBL20076582 0.72 SLC9A1 (0.43) SLC9A1
SCHEMBL20076622 0.71 SLC9A1 (0.35) SLC9A1
SCHEMBL20076385 0.69 SLC9A1 (0.59) SLC9A1HTR2AHTR2CHTR2B
SCHEMBL20076832 0.69 SLC9A1 (0.43) SLC9A1HTR2AHTR2CHTR2B
SCHEMBL20076386 0.69 SLC9A1 (0.39) SLC9A1
SCHEMBL20076828 0.68 SLC9A1 (0.37) SLC9A1
SCHEMBL20076406 0.67 MEN1 (0.30)
SCHEMBL20076813 0.67 ALDH1A1 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018071327-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO DOW AGROSCIENCES LLC (US) 2018-04-19 WO disclosed