SCHEMBL20076816

SCHEMBL20076816

CC1[C@H](c2cc(Cl)c(Cl)c(Cl)c2)C1(Cl)Cl

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.36
CYP3A4 P08684 2/20 0.33
HPGD P15428 1/20 0.33
CRHBP P24387 1/20 0.33
CRHR2 Q13324 1/20 0.33
HSD17B10 Q99714 1/20 0.33
AHR P35869 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21022562 1.00 ALDH1A1 (0.36) ALDH1A1CYP3A4HPGDCRHBPCRHR2
SCHEMBL20051055 0.86
SCHEMBL20050347 0.83
SCHEMBL20051061 0.82 NOTUM (0.35)
SCHEMBL18154019 0.79 SLC9A1 (0.42) CYP3A4
SCHEMBL21586870 0.74 CYP2D6 (0.40) ALDH1A1
SCHEMBL18143953 0.72 ALDH1A1 (0.32) ALDH1A1CYP3A4HPGDCRHBPCRHR2
SCHEMBL18143950 0.72 ALDH1A1 (0.32) ALDH1A1CYP3A4HPGDCRHBPCRHR2
SCHEMBL18143948 0.72 ALDH1A1 (0.32) ALDH1A1CYP3A4HPGDCRHBPCRHR2
SCHEMBL25842757 0.72 ALDH1A1 (0.32) ALDH1A1CYP3A4HPGDCRHBPCRHR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018071327-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO DOW AGROSCIENCES LLC (US) 2018-04-19 WO disclosed