SCHEMBL20076844

SCHEMBL20076844

C=C(C)Nc1cccc(F)c1N

nearest known ligand 0.54

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 3/20 0.54
ALDH1A1 P00352 4/20 0.40
GAA P10253 1/20 0.38
RAB9A P51151 3/20 0.37
SMN1; SMN2 Q16637 3/20 0.37
NPC1 O15118 1/20 0.37
HPGD P15428 1/20 0.36
KMT2A Q03164 2/20 0.35
MEN1 O00255 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
EGFR P00533 1/20 0.35
NPSR1 Q6W5P4 1/20 0.34
KDM4E B2RXH2 1/20 0.34
ALOX12 P18054 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20051714 0.81 HDAC1 (0.70) HDAC1ALDH1A1GAARAB9ASMN1; SMN2
SCHEMBL11946846 0.76 HDAC1 (0.50) HDAC1ALDH1A1GAARAB9ASMN1; SMN2
SCHEMBL15551470 0.76 HDAC1 (0.55) HDAC1ALDH1A1GAARAB9ASMN1; SMN2
SCHEMBL1861299 0.74 HDAC1 (0.45) HDAC1ALDH1A1GAARAB9ASMN1; SMN2
SCHEMBL12264141 0.74 HDAC1 (0.54) HDAC1ALDH1A1GAARAB9ASMN1; SMN2
SCHEMBL23465740 0.73 HDAC1 (0.34) HDAC1GAARAB9ASMN1; SMN2NPC1
SCHEMBL23843372 0.72 CYP3A4 (0.48) ALDH1A1GAARAB9ANPC1KMT2A
SCHEMBL20051277 0.71 HDAC1 (0.51) HDAC1ALDH1A1RAB9ASMN1; SMN2NPC1
SCHEMBL28121161 0.71 CES2 (0.38) HDAC1ALDH1A1GAASMN1; SMN2KMT2A
SCHEMBL2951453 0.71 ALDH1A1 (0.43) HDAC1ALDH1A1GAASMN1; SMN2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018071327-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO DOW AGROSCIENCES LLC (US) 2018-04-19 WO disclosed