SCHEMBL20076856

SCHEMBL20076856

CCCC(/C=C/c1ccc(F)c(Cl)c1)CCC

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.43
TSHR P16473 2/20 0.35
KMT2A Q03164 2/20 0.35
MEN1 O00255 1/20 0.35
NFE2L2 Q16236 1/20 0.34
CHAT P28329 1/20 0.34
KDM4E B2RXH2 1/20 0.33
ALDH3A1 P30838 1/20 0.32
ALDH1A3 P47895 1/20 0.32
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
LMNA P02545 1/20 0.31
MAOB P27338 1/20 0.31
HDAC3 O15379 1/20 0.31
HDAC4 P56524 1/20 0.31
HDAC1 Q13547 1/20 0.31
HDAC7 Q8WUI4 1/20 0.31
HDAC2 Q92769 1/20 0.31
HDAC10 Q969S8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21021438 0.85 CHAT (0.44) KMT2ACHAT
SCHEMBL20076868 0.78 ALDH1A1 (0.30)
SCHEMBL13597784 0.78 TRPA1 (0.41) TRPA1TSHRKMT2AMEN1NFE2L2
SCHEMBL30739641 0.77 TRPA1 (0.42) TRPA1TSHRKMT2AMEN1NFE2L2
SCHEMBL18144160 0.77 TRPA1 (0.42) TRPA1TSHRKMT2AMEN1NFE2L2
SCHEMBL18144158 0.77 TRPA1 (0.42) TRPA1TSHRKMT2AMEN1NFE2L2
SCHEMBL21021651 0.75
SCHEMBL29371144 0.75 TRPA1 (0.48) TRPA1TSHRKMT2AMEN1NFE2L2
SCHEMBL10160933 0.75 TRPA1 (0.48) TRPA1TSHRKMT2AMEN1NFE2L2
SCHEMBL21021677 0.73 PTGS1 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018071327-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO DOW AGROSCIENCES LLC (US) 2018-04-19 WO disclosed