Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 9/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | BACE2 | Q9Y5Z0 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | CTSD | P07339 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20076450 | 0.86 | ALDH1A1 (0.37) | BACE1RAB9AMEN1ALDH1A1KMT2A | |
| SCHEMBL21021640 | 0.86 | RAB9A (0.34) | BACE1NPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL20076551 | 0.81 | BACE1 (0.38) | BACE1NPC1RAB9ASMN1; SMN2BACE2 | |
| SCHEMBL21021233 | 0.77 | RAB9A (0.36) | NPC1RAB9AMEN1ALDH1A1KMT2A | |
| SCHEMBL21021582 | 0.76 | MEN1 (0.33) | BACE1NPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL21021632 | 0.75 | RAB9A (0.39) | NPC1RAB9ASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL20076414 | 0.73 | ALDH1A1 (0.39) | NPC1RAB9ASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL20076953 | 0.72 | NPC1 (0.32) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL20076532 | 0.72 | NPC1 (0.36) | BACE1NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL21021987 | 0.72 | KDR (0.32) | BACE1NPC1RAB9ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018071327-A1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2018-04-19 | — | — | WO | disclosed |