Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLRMT | O00411 | 1/20 | 0.37 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.36 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20078677 | 0.89 | TMPRSS2 (0.40) | POLRMTTMPRSS2 | |
| SCHEMBL24789693 | 0.88 | POLRMT (0.38) | POLRMTTMPRSS2 | |
| SCHEMBL24074599 | 0.88 | POLRMT (0.49) | POLRMTTMPRSS2RNASEL | |
| SCHEMBL18666920 | 0.87 | TMPRSS2 (0.46) | POLRMTTMPRSS2 | |
| SCHEMBL24791772 | 0.87 | POLRMT (0.37) | POLRMTTMPRSS2 | |
| SCHEMBL24606306 | 0.83 | TMPRSS2 (0.41) | POLRMTTMPRSS2 | |
| SCHEMBL12454229 | 0.83 | POLRMT (0.38) | POLRMTTMPRSS2 | |
| SCHEMBL10153929 | 0.81 | TMPRSS2 (0.44) | POLRMTTMPRSS2 | |
| SCHEMBL20144212 | 0.80 | TMPRSS2 (0.37) | POLRMTTMPRSS2 | |
| SCHEMBL18636432 | 0.79 | TMPRSS2 (0.36) | POLRMTTMPRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9949994-B2 | Methods for treating Filoviridae virus infections | GILEAD SCIENCES, INC. (US) | 2018-04-24 | — | — | US | disclosed |