Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.40 |
| ▸ | POLRMT | O00411 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20078643 | 0.89 | POLRMT (0.37) | TMPRSS2POLRMT | |
| SCHEMBL24606306 | 0.86 | TMPRSS2 (0.41) | TMPRSS2POLRMTPIK3CDRIPK1 | |
| SCHEMBL10153929 | 0.85 | TMPRSS2 (0.44) | TMPRSS2POLRMTPIK3CD | |
| SCHEMBL24789693 | 0.83 | POLRMT (0.38) | TMPRSS2POLRMTPIK3CD | |
| SCHEMBL24074599 | 0.83 | POLRMT (0.49) | TMPRSS2POLRMT | |
| SCHEMBL23034569 | 0.82 | TMPRSS2 (0.36) | TMPRSS2POLRMT | |
| SCHEMBL18636432 | 0.82 | TMPRSS2 (0.36) | TMPRSS2POLRMTRIPK1 | |
| SCHEMBL24791772 | 0.82 | POLRMT (0.37) | TMPRSS2POLRMTPIK3CD | |
| SCHEMBL20078672 | 0.81 | TMPRSS2 (0.36) | TMPRSS2RIPK1 | |
| SCHEMBL12454229 | 0.81 | POLRMT (0.38) | TMPRSS2POLRMTPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9949994-B2 | Methods for treating Filoviridae virus infections | GILEAD SCIENCES, INC. (US) | 2018-04-24 | — | — | US | disclosed |