Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | EGFR | P00533 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.41 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6306638 | 0.83 | KDM4E (0.57) | KDM4ELMNAHTTEGFRHSD17B10 | |
| SCHEMBL19301871 | 0.81 | KDM4E (0.54) | KDM4ELMNAHTTEGFRHSD17B10 | |
| SCHEMBL16011809 | 0.73 | ALK (0.54) | EGFRPTK6ERBB2 | |
| SCHEMBL28665437 | 0.72 | CA5A (0.47) | KDM4ELMNAHTTEGFRHSD17B10 | |
| SCHEMBL676055 | 0.70 | CA5A (0.62) | KDM4ELMNAHTTHSD17B10CYP1A2 | |
| SCHEMBL5440852 | 0.70 | POLB (0.42) | KDM4ELMNAHTTEGFRHSD17B10 | |
| Ammonia Solution, Strong SCHEMBL28371640 | 0.70 | KDM4E (0.93) | KDM4ELMNAHTTHSD17B10CYP1A2 | |
| SCHEMBL28629227 | 0.70 | KDM4E (0.64) | KDM4ELMNAHTTEGFRHSD17B10 | |
| SCHEMBL31656035 | 0.69 | KDM4E (0.51) | KDM4ELMNAHTTEGFRHSD17B10 | |
| SCHEMBL31053694 | 0.69 | HSD17B10 (0.46) | KDM4ELMNAHTTEGFRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9951061-B2 | CaMKII inhibitors and uses thereof | ALLOSTEROS THERAPEUTICS, INC. (US) | 2018-04-24 | — | — | US | disclosed |