Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.64 |
| ▸ | LMNA | P02545 | 4/20 | 0.64 |
| ▸ | MAPT | P10636 | 4/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.64 |
| ▸ | TSHR | P16473 | 3/20 | 0.64 |
| ▸ | POLB | P06746 | 3/20 | 0.64 |
| ▸ | HPGD | P15428 | 3/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.64 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | CASP1 | P29466 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | CASP7 | P55210 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.54 |
| ▸ | TOP2A | P11388 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17286169 | 0.82 | KDM4E (0.51) | KDM4EHSD17B10LMNAMAPTALDH1A1 | |
| SCHEMBL6306638 | 0.72 | KDM4E (0.57) | KDM4EHSD17B10LMNAMAPTALDH1A1 | |
| SCHEMBL6215793 | 0.72 | KDM4E (0.56) | KDM4EHSD17B10LMNAMAPTALDH1A1 | |
| SCHEMBL20982276 | 0.72 | ALDH1A1 (0.55) | KDM4EHSD17B10LMNAMAPTALDH1A1 | |
| SCHEMBL8390746 | 0.71 | GPR3 (0.50) | KDM4EHSD17B10LMNAMAPTALDH1A1 | |
| SCHEMBL31656035 | 0.71 | KDM4E (0.51) | KDM4EHSD17B10LMNAMAPTALDH1A1 | |
| SCHEMBL17047835 | 0.71 | EGFR (0.49) | KDM4EHSD17B10LMNAMAPTALDH1A1 | |
| SCHEMBL30254691 | 0.71 | EGFR (0.49) | KDM4EHSD17B10LMNAMAPTALDH1A1 | |
| SCHEMBL278729 | 0.71 | RAB9A (1.00) | KDM4EHSD17B10LMNAMAPTALDH1A1 | |
| SCHEMBL29572859 | 0.71 | RAB9A (1.00) | KDM4EHSD17B10LMNAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113336749-B | Preparation method of indoloquinoline compound | 湖北工业大学 | 2022-04-29 | — | — | CN | disclosed |
| CN-113336749-A | Preparation method of indoloquinoline compound | 湖北工业大学 | 2021-09-03 | — | — | CN | disclosed |