Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | FTO | Q9C0B1 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.56 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.56 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16772402 | 0.84 | NPSR1 (0.45) | MAPTFTOMEN1KMT2ATDP1 | |
| SCHEMBL20468616 | 0.81 | MAPT (0.39) | MAPTFTOMEN1KMT2ATDP1 | |
| SCHEMBL16755703 | 0.81 | CYP3A4 (0.44) | MAPTMEN1KMT2ATDP1HPGD | |
| Fluorescein SCHEMBL4824411 | 0.73 | FTO (0.97) | MAPTFTOMEN1KMT2ATDP1 | |
| Fluorescein SCHEMBL4824399 | 0.73 | FTO (0.97) | MAPTFTOMEN1KMT2ATDP1 | |
| SCHEMBL16772538 | 0.72 | MEN1 (0.59) | MAPTFTOMEN1KMT2ATDP1 | |
| Fluorescein SCHEMBL16533 | 0.71 | FTO (1.00) | MAPTFTOMEN1KMT2ATDP1 | |
| Fluorescein SCHEMBL29371199 | 0.71 | FTO (1.00) | MAPTFTOMEN1KMT2ATDP1 | |
| Fluorescein SCHEMBL29388667 | 0.71 | FTO (1.00) | MAPTFTOMEN1KMT2ATDP1 | |
| Fluorescein SCHEMBL30272223 | 0.71 | FTO (1.00) | MAPTFTOMEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2861580-B1 | SECA INHIBITORS AND METHODS OF MAKING AND USING THEREOF | UNIV GEORGIA STATE RES FOUND (US) | 2018-04-25 | — | — | EP | disclosed |