SCHEMBL2008034

SCHEMBL2008034

CCOC(=O)c1ccccc1Nc1ccccc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.71
ALOX15 P16050 1/20 0.71
CDC25B P30305 5/20 0.65
CDC25A P30304 1/20 0.65
CDC25C P30307 1/20 0.65
TSHR P16473 3/20 0.62
KMT2A Q03164 1/20 0.61
ALDH1A1 P00352 3/20 0.59
METTL3 Q86U44 1/20 0.59
KDM4E B2RXH2 3/20 0.58
HSD17B10 Q99714 2/20 0.58
MAPK10 P53779 1/20 0.58
ATM Q13315 1/20 0.58
LMNA P02545 1/20 0.57
CYP1A2 P05177 1/20 0.57
CYP2C19 P33261 1/20 0.57
CASP3 P42574 1/20 0.57
SENP8 Q96LD8 1/20 0.57
SENP7 Q9BQF6 1/20 0.57
SENP6 Q9GZR1 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10833818 0.89 CDC25B (0.65) MAPTALOX15CDC25BCDC25ACDC25C
SCHEMBL4544856 0.89 CDC25B (0.60) MAPTALOX15CDC25BCDC25ACDC25C
SCHEMBL3630708 0.88 KDM4E (0.67) MAPTALOX15CDC25BCDC25ACDC25C
SCHEMBL6569817 0.88 MAPT (0.67) MAPTALOX15CDC25BCDC25ACDC25C
SCHEMBL5846272 0.87 ATM (0.62) MAPTALOX15CDC25BCDC25ACDC25C
SCHEMBL10834780 0.87 ALDH1A1 (0.65) MAPTALOX15CDC25BCDC25ACDC25C
SCHEMBL1963500 0.87 ATM (0.55) MAPTALOX15CDC25BCDC25ACDC25C
SCHEMBL28849406 0.86 TSHR (0.61) CDC25BCDC25ACDC25CTSHRKMT2A
SCHEMBL22556586 0.84 CDC25B (0.56) MAPTALOX15CDC25BCDC25ACDC25C
SCHEMBL6191137 0.84 CDC25B (0.55) MAPTALOX15CDC25BCDC25ACDC25C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103435549-A 5-methyl-7-amino-5H,7H-dibenzo[b,d]azepin-6-ketone preparation method HUIFEICHEM WUXI PHARMATECH CO LTD 2013-12-11 CN claimed
US-20070166341-A1 Solid volatile composition and method and system for making the same INTERNATIONAL ARTS & SCIENCE GROUP, INC. 2007-07-19 US claimed
CN-118159258-A Composition containing caryophyllene 三生医药株式会社 2024-06-07 CN disclosed
CN-117120042-A Seamless capsule capable of stably disintegrating even in high-temperature and high-humidity environment and method for producing same 森下仁丹株式会社 2023-11-24 CN disclosed
CN-110869348-B Pyrrole compound, perfume composition, and cosmetic containing the same 长谷川香料株式会社 2023-09-12 CN disclosed
CN-110302727-A A kind of grade microcapsules and preparation method thereof 江南大学 2019-10-08 CN disclosed
CN-109208328-A Aqueous fabric soft compound 广州蓝月亮实业有限公司 2019-01-15 CN disclosed
EP-3422853-A1 INSECT REPELLENT FMC Corporation (US) 2019-01-09 EP disclosed
CN-105585601-B Anti-aging skin external composition and preparation method thereof 株式会社林原 2018-11-13 CN disclosed
CN-107880545-A Resin combination, the manufacture method of solidfied material and solidfied material 东京应化工业株式会社 2018-04-06 CN disclosed
CN-107349134-A Improved hidroschesis/deodorant compositions ISP投资公司 2017-11-17 CN disclosed
EP-1004654-A2 Adjuvants and methods for raising intracellular calcium ion concentration Takasago International Corporation (JP) 2000-05-31 EP disclosed
US-5672352-A Methods of identifying the avian repellent effects of a compound and methods of repelling birds from materials susceptible to consumption by birds MONELL CHEMICAL SENSES CENTER (US) 1997-09-30 US disclosed
US-5296226-A Mixture of chemical repellent, anionic surfactant or emulsifier, water DOLPHIN TRUST (US) 1994-03-22 US disclosed
US-4548764-A Insect repellent, pheremonal, animal repellent, diagnostic or aroma enhancing compositions containing poly(epsilon caprolactone) having embedded therein functional substances INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1985-10-22 US disclosed
US-4543367-A Process for forming functional fluid and solid-containing thermoplastic films, uses thereof and process for producing same INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1985-09-24 US disclosed
US-4542162-A EXTRUSION, FOAMING INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1985-09-17 US disclosed
US-4521541-A Process for forming functional fluid and solid-containing thermoplastic films, uses thereof and process for producing same INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1985-06-04 US disclosed
US-4496467-A Insect repellent, pheremonal, animal repellent diagnostic and/or aroma augmenting or enhancing compositions and articles containing at least a major proportion of poly(epsilon caprolactone)homopolymers, and having imbedded therein one or more functional INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1985-01-29 US disclosed
US-4469613-A SUSTAINED RELEASE OF PERFUME INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1984-09-04 US disclosed