SCHEMBL4544856

SCHEMBL4544856

CCOC(=O)c1ccccc1Nc1nc(Nc2ccccc2)nc(Nc2ccccc2)n1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDC25B P30305 6/20 0.60
CDC25A P30304 1/20 0.60
CDC25C P30307 1/20 0.60
MAPT P10636 1/20 0.56
ALOX15 P16050 1/20 0.56
HTT P42858 1/20 0.55
ILK Q13418 1/20 0.54
AURKA O14965 1/20 0.53
TSHR P16473 2/20 0.53
KMT2A Q03164 2/20 0.53
CSF1R P07333 1/20 0.53
ALDH1A1 P00352 1/20 0.52
METTL3 Q86U44 1/20 0.52
TP53 P04637 1/20 0.52
HPGD P15428 1/20 0.52
KDM4E B2RXH2 3/20 0.51
HSD17B10 Q99714 2/20 0.51
RAB9A P51151 2/20 0.51
MEN1 O00255 1/20 0.51
THRB P10828 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4544815 0.89 CDC25B (0.57) CDC25BCDC25ACDC25CMAPTAURKA
SCHEMBL2008034 0.89 MAPT (0.71) CDC25BCDC25ACDC25CMAPTALOX15
SCHEMBL4544793 0.86 MAPT (0.77) MAPTALOX15HTTAURKAKMT2A
SCHEMBL10833818 0.79 CDC25B (0.65) CDC25BCDC25ACDC25CMAPTALOX15
SCHEMBL28849406 0.79 TSHR (0.61) CDC25BCDC25ACDC25CHTTTSHR
SCHEMBL14079358 0.78 MAPT (0.63) MAPTALOX15HTTAURKAKMT2A
SCHEMBL19088133 0.78 MEN1 (0.64) CDC25BMAPTALOX15HTTAURKA
SCHEMBL4544847 0.78 MEN1 (0.64) MAPTALOX15HTTAURKAKMT2A
SCHEMBL3630708 0.78 KDM4E (0.67) CDC25BCDC25ACDC25CMAPTALOX15
SCHEMBL6569817 0.77 MAPT (0.67) CDC25BCDC25ACDC25CMAPTALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9223070-B2 Optical film, polarizing plate equipped with the optical film, process for manufacture of the polarizing plate, and liquid crystal display device Konica Minolta, Inc. (JP) 2015-12-29 US disclosed
US-9110243-B2 Laminate film, optically compensatory film, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2015-08-18 US disclosed
US-9103988-B2 Liquid-crystal display device FUJIFILM CORPORATION (JP) 2015-08-11 US disclosed
US-8976325-B2 VA-mode liquid-crystal display device FUJIFILM CORPORATION (JP) 2015-03-10 US disclosed
US-20150033984-A1 CELLULOSE ACYLATE FILM, POLARIZING PLATE, MANUFACTURING METHOD OF POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2015-02-05 US disclosed
US-8947621-B2 Liquid crystal display device comprising a front plate having a lamda/4 plate that includes a hard coat layer and method for manufacturing the same KONICA MINOLTA ADVANCED LAYERS, INC. (JP) 2015-02-03 US disclosed
US-8681295-B2 VA-mode liquid-crystal display device FUJIFILM CORPORATION (JP) 2014-03-25 US disclosed
US-20130293812-A1 OPTICAL FILM, POLARIZING PLATE EQUIPPED WITH THE OPTICAL FILM, PROCESS FOR MANUFACTURE OF THE POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE Konica Minolta, Inc. (JP) 2013-11-07 US disclosed
US-20130169897-A1 METHOD FOR MANUFACTURING LIQUID CRYSTAL DISPLAY DEVICE WITH FRONT PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE WITH FRONT PLATE KONICA MINOLTA ADVANCED LAYERS, INC. (JP) 2013-07-04 US disclosed
US-8477273-B2 VA-mode liquid-crystal display device FUJIFILM CORPORATION (JP) 2013-07-02 US disclosed
US-20080204644-A1 Liquid crystal display device FUJIFILM CORPORATION (JP) 2008-08-28 US disclosed
US-20080198303-A1 Polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2008-08-21 US disclosed
US-20080192192-A1 Optical film and polarizing plate FUJIFILM CORPORATION (JP) 2008-08-14 US disclosed
US-20080174724-A1 Liquid crystal display device, optical film and polarizing plate FUJIFILM CORPORATION (JP) 2008-07-24 US disclosed
US-20080158488-A1 Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2008-07-03 US disclosed
US-20080143928-A1 Polarizing Plate and Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2008-06-19 US disclosed
US-20080137014-A1 Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2008-06-12 US disclosed
US-20080013173-A1 METHOD OF MANUFACTURING A POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE KONICA MINOLTA OPTO, INC. (JP) 2008-01-17 US disclosed
US-20080013173-A1 METHOD OF MANUFACTURING A POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE KONICA MINOLTA OPTO, INC. (JP) 2008-01-17 US disclosed
WO-2007023990-A1 LIQUID CRYSTAL DISPLAY DEVICE FUJI FILM CORPORATION (JP) 2007-03-01 WO disclosed