Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | RARB | P10826 | 4/20 | 0.41 |
| ▸ | RARA | P10276 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.37 |
| ▸ | LSS | P48449 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL815645 | 0.94 | THRB (0.47) | THRBTSHRALDH1A1CYP3A4RARB | |
| SCHEMBL14088550 | 0.91 | THRB (0.48) | THRBTSHRALDH1A1CYP3A4RARB | |
| SCHEMBL20082220 | 0.89 | TSHR (0.51) | THRBTSHRALDH1A1CYP3A4RARB | |
| SCHEMBL20082190 | 0.89 | TSHR (0.51) | THRBTSHRALDH1A1CYP3A4RARB | |
| SCHEMBL20082224 | 0.89 | TSHR (0.51) | THRBTSHRALDH1A1CYP3A4RARB | |
| SCHEMBL18200224 | 0.87 | HDAC1 (0.47) | THRBTSHRALDH1A1CYP3A4RARB | |
| SCHEMBL17250029 | 0.87 | HDAC1 (0.47) | THRBTSHRALDH1A1CYP3A4RARB | |
| SCHEMBL23227543 | 0.85 | THRB (0.42) | THRBTSHRALDH1A1CYP3A4RARB | |
| SCHEMBL12173355 | 0.84 | THRB (0.49) | THRBTSHRALDH1A1CYP3A4RARB | |
| SCHEMBL15834357 | 0.84 | MMP2 (0.45) | THRBALDH1A1RARBRARAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3312258-A1 | POLYMERIZABLE COMPOSITION AND OPTICALLY ANISOTROPIC BODY USING SAME | DIC Corporation (JP) | 2018-04-25 | — | — | EP | disclosed |