Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CTSV | O60911 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28068351 | 0.90 | ALDH1A1 (0.62) | ALDH1A1CYP3A4ALOX15TDP1TP53 | |
| SCHEMBL11622455 | 0.88 | ALDH1A1 (0.55) | ALDH1A1CYP3A4ALOX15TDP1TP53 | |
| SCHEMBL9420470 | 0.86 | ALDH1A1 (0.57) | ALDH1A1CYP3A4ALOX15TDP1TP53 | |
| SCHEMBL9420573 | 0.86 | ALDH1A1 (0.57) | ALDH1A1CYP3A4ALOX15TDP1TP53 | |
| SCHEMBL6304897 | 0.84 | ALDH1A1 (0.55) | ALDH1A1CYP3A4ALOX15TDP1TP53 | |
| SCHEMBL6304900 | 0.84 | ALDH1A1 (0.55) | ALDH1A1CYP3A4ALOX15TDP1TP53 | |
| SCHEMBL3387313 | 0.84 | ALDH1A1 (0.55) | ALDH1A1CYP3A4ALOX15TDP1TP53 | |
| SCHEMBL2557500 | 0.82 | ALDH1A1 (0.60) | ALDH1A1CYP3A4ALOX15TDP1TP53 | |
| SCHEMBL28428327 | 0.82 | ALDH1A1 (0.60) | ALDH1A1CYP3A4ALOX15TDP1TP53 | |
| SCHEMBL27882095 | 0.82 | ALDH1A1 (0.60) | ALDH1A1CYP3A4ALOX15TDP1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7960181-B2 | Chromoionophore and method of determining potassium ions | OPTI MEDICAL SYSTEMS (US) | 2011-06-14 | — | — | US | disclosed |
| WO-2007131042-A2 | CHROMOIONOPHORE AND METHOD OF DETERMINING POTASSIUM IONS | OPTI MEDICAL SYSTEMS, INC (US) | 2007-11-15 | — | — | WO | disclosed |
| US-20070259443-A1 | CHROMOIONOPHORE AND METHOD OF DETERMINING POTASSIUM IONS | OPTI MEDICAL SYSTEMS, INC. | 2007-11-08 | — | — | US | disclosed |