Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 4/20 | 0.33 |
| ▸ | TOP2B | Q02880 | 4/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 2/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1289943 | 0.92 | TOP2A (0.34) | TOP2ATOP2BNOTUMRORCDGAT1 | |
| Potassium Ion SCHEMBL1290141 | 0.82 | — | — | |
| SCHEMBL1290126 | 0.82 | NOTUM (0.34) | NOTUMRORCDGAT1 | |
| SCHEMBL1290023 | 0.82 | TOP2A (0.36) | TOP2ATOP2BNOTUMRORC | |
| SCHEMBL20083202 | 0.81 | RORC (0.32) | TOP2ATOP2BNOTUMRORC | |
| SCHEMBL1290104 | 0.80 | KDM4E (0.36) | — | |
| SCHEMBL20960262 | 0.79 | TOP2A (0.38) | TOP2ATOP2BNOTUMRORC | |
| SCHEMBL1290323 | 0.79 | NOTUM (0.37) | TOP2ATOP2BNOTUMRORC | |
| SCHEMBL1290214 | 0.79 | NOTUM (0.32) | TOP2ATOP2BNOTUMRORC | |
| SCHEMBL12502227 | 0.79 | TOP2A (0.45) | TOP2ATOP2BNOTUMRORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3312176-A1 | ANTIMICROBIAL 4-OXOQUINOLIZINES | Emergent Product Development Gaithersburg Inc. (US) | 2018-04-25 | — | — | EP | disclosed |