SCHEMBL2008381

SCHEMBL2008381

C=C(C)C(=O)OCCN(C)C.C=C(CC)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.46
TSHR P16473 4/20 0.45
CHRM1 P11229 2/20 0.42
CHRM2 P08172 1/20 0.42
CHRM4 P08173 1/20 0.42
CHRM5 P08912 1/20 0.42
CHRNB2 P17787 1/20 0.42
CHRM3 P20309 1/20 0.42
CHRNA4 P43681 1/20 0.42
DNM1 Q05193 1/20 0.38
POLB P06746 1/20 0.35
APEX1 P27695 1/20 0.35
HTT P42858 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
BCHE P06276 1/20 0.34
ALDH1A1 P00352 3/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9667032 0.90 TSHR (0.63) THRBTSHRCHRM1CHRM2CHRM4
SCHEMBL3174745 0.89 DNM1 (0.50) THRBTSHRCHRM1CHRM2CHRM4
Propionic Acid SCHEMBL19150091 0.88 THRB (0.50) THRBTSHRCHRM1CHRM2CHRM4
Methacrylic Acid SCHEMBL11969913 0.88 THRB (0.48) THRBTSHRCHRM1CHRM2CHRM4
Methacrylic Acid SCHEMBL319586 0.88 THRB (0.48) THRBTSHRCHRM1CHRM2CHRM4
Acetic Acid SCHEMBL4066016 0.86 CHRM1 (0.50) THRBTSHRCHRM1CHRM2CHRM4
Propane SCHEMBL6811290 0.86 THRB (0.55) THRBTSHRCHRM1CHRM2CHRM4
SCHEMBL28671752 0.86 CHRM2 (0.54) THRBTSHRCHRM1CHRM2CHRM4
SCHEMBL14984 0.86 CHRM2 (0.54) THRBTSHRCHRM1CHRM2CHRM4
SCHEMBL5139768 0.86 THRB (0.45) THRBTSHRCHRM1CHRM2CHRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1932511-A2 Peeling process based on a cationic microgel L'OREAL (FR) 2008-06-18 EP claimed
US-6423461-B1 INORGANIC POLYMER AND ORGANOMETALLIC POLYMER BLEND OF POLYFERROCENES AND POLYPHOSPHAZENES XEROX CORPORATION 2002-07-23 US claimed
US-6037091-A Carrier with ferrocene containing polymer XEROX CORPORATION (US) 2000-03-14 US claimed
US-6004712-A CORE AND THEREOVER A POLYMER OF (1) METHYLMETHACRYLATE AND A MONOALKYL AMINOALKYL METHACRYLATE, OR (2) A POLYMER OF METHYLMETHACRYLATE AND DIALKYLAMINOALKYL METHACRYLATE, TONER AND DEVELOPER XEROX CORPORATION (US) 1999-12-21 US claimed
US-20170298295-A1 TREATMENT COMPOSITIONS PROCTER & GAMBLE (US) 2017-10-19 US disclosed
US-7960544-B2 Useful indole compounds IRONWOOD PHARMACEUTICALS, INC. (US) 2011-06-14 US disclosed
US-7862970-B2 Toner compositions with amino-containing polymers as surface additives XEROX CORPORATION (US) 2011-01-04 US disclosed
EP-1932511-A2 Peeling process based on a cationic microgel L'OREAL (FR) 2008-06-18 EP disclosed
US-7374849-B2 Coated carrier XEROX CORPORATION (US) 2008-05-20 US disclosed
US-20060257775-A1 Toner compositions with amino-containing polymers as surface additives XEROX CORPORATION (US) 2006-11-16 US disclosed
US-20060166125-A1 Coated carrier XEROX CORPORATION 2006-07-27 US disclosed
US-6698510-B2 Article and method for temperature regulation using a thermosensitive reactive hydrogel material MIDE TECHNOLOGY CORPORATION 2004-03-02 US disclosed
US-5840338-A THERMAL AND CHEMICAL STABILITY MEDLOGIC GLOBAL LIMITED (GB) 1998-11-24 US disclosed
EP-0853474-A2 CHEMO-MECHANICAL EXPANSION DELIVERY SYSTEM Gel Sciences, Inc. (US) 1998-07-22 EP disclosed
WO-1998017260-A1 CHEMO-MECHANICAL EXPANSION DELIVERY SYSTEM MEDLOGIC GLOBAL CORPORATION (US) 1998-04-30 WO disclosed
EP-0831792-A2 APPARATUS AND METHOD FOR DELIVERING A BIOLOGICALLY ACTIVE COMPOUND INTO A BIOLOGICAL ENVIRONMENT Gel Sciences, Inc. (US) 1998-04-01 EP disclosed
WO-1998002146-A2 CHEMO-MECHANICAL EXPANSION DELIVERY SYSTEM MEDLOGIC GLOBAL CORPORATION (US) 1998-01-22 WO disclosed
US-5651979-A Apparatus and method for delivering a biologically active compound into a biological environment GEL SCIENCES, INC. (US) 1997-07-29 US disclosed
WO-1996040082-A2 APPARATUS AND METHOD FOR DELIVERING A BIOLOGICALLY ACTIVE COMPOUND INTO A BIOLOGICAL ENVIRONMENT GEL SCIENCES, INC. (US) 1996-12-19 WO disclosed
WO-1996002276-A9 NOVEL POLYMER GEL NETWORKS AND METHODS OF USE 1996-02-29 WO disclosed