Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20084128 | 0.90 | RAB9A (0.32) | RAB9AALDH1A1HPGDNPC1L3MBTL1 | |
| SCHEMBL20084066 | 0.89 | ALDH1A1 (0.30) | RAB9AALDH1A1HPGD | |
| SCHEMBL20084129 | 0.89 | — | — | |
| SCHEMBL20084127 | 0.86 | ALDH1A1 (0.30) | RAB9AALDH1A1HPGD | |
| SCHEMBL20084119 | 0.85 | HPGD (0.35) | RAB9AALDH1A1HPGDNPC1L3MBTL1 | |
| SCHEMBL20084272 | 0.85 | ALDH1A1 (0.31) | RAB9AALDH1A1HPGD | |
| SCHEMBL21572150 | 0.85 | ALDH1A1 (0.31) | RAB9AALDH1A1HPGD | |
| SCHEMBL20084029 | 0.83 | HPGD (0.34) | RAB9AALDH1A1HPGDNPC1L3MBTL1 | |
| SCHEMBL20085209 | 0.82 | HPGD (0.39) | RAB9AALDH1A1HPGDNPC1L3MBTL1 | |
| SCHEMBL20084311 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3312172-B1 | AMINOPYRAZOLE DERIVATIVES USEFUL AS SRC KINASE INHIBITORS | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2020-05-06 | — | — | EP | disclosed |
| EP-3312172-A1 | AMINOPYRAZOLE DERIVATIVES | Chugai Seiyaku Kabushiki Kaisha (JP) | 2018-04-25 | — | — | EP | disclosed |