Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.38 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.38 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.38 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL699014 | 0.86 | PTGS1 (0.47) | SMN1; SMN2NPSR1HSD17B10PTGS1KDM4E | |
| SCHEMBL699294 | 0.83 | LMNA (0.51) | SMN1; SMN2NPSR1ALDH1A1MEN1MAPT | |
| SCHEMBL698268 | 0.82 | TAS1R3 (0.37) | ALDH1A1MEN1MAPTKMT2ATAS1R3 | |
| SCHEMBL2111601 | 0.80 | LMNA (0.50) | SMN1; SMN2NPSR1ALDH1A1MEN1MAPT | |
| SCHEMBL699065 | 0.79 | TAS1R3 (0.36) | MEN1MAPTKMT2ATAS1R3TAS1R1 | |
| SCHEMBL2005866 | 0.79 | SMN1; SMN2 (0.49) | SMN1; SMN2NPSR1HSD17B10PTGS1KDM4E | |
| SCHEMBL1360387 | 0.77 | PTGS1 (0.45) | SMN1; SMN2NPSR1HSD17B10PTGS1KDM4E | |
| SCHEMBL13875600 | 0.75 | KDM4E (0.45) | SMN1; SMN2NPSR1HSD17B10PTGS1KDM4E | |
| SCHEMBL4182215 | 0.75 | PTGS1 (0.47) | SMN1; SMN2NPSR1HSD17B10PTGS1KDM4E | |
| SCHEMBL4178309 | 0.75 | PTGS1 (0.45) | SMN1; SMN2NPSR1HSD17B10PTGS1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2535327-A1 | Insecticidal 3-acylaminobenzanilides | Bayer CropScience AG (DE) | 2012-12-19 | — | — | EP | disclosed |
| US-7964735-B2 | Insecticidal 3-acylaminobenzanilides | BAYER CROPSCIENCE AG (DE) | 2011-06-21 | — | — | US | disclosed |
| US-20090215623-A1 | Insecticidal 3-acylaminobenzanilides | BAYER CROPSCIENCE AG (DE) | 2009-08-27 | — | — | US | disclosed |
| EP-1912933-A1 | INSECTICIDAL 3-ACYLAMINOBENZANILIDES | Bayer CropScience AG (DE) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007017075-A1 | INSECTICIDAL 3-ACYLAMINOBENZANILIDES | BAYER CROPSCIENCE AG (DE) | 2007-02-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090215623-A1 | Insecticidal 3-acylaminobenzanilides | CBR3, AADAC, DDT | SMN1; SMN2 4300/4885NPSR1 1017/4885HSD17B10 484/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.