Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 5/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20085209 | 0.91 | HPGD (0.39) | HPGDLMNANPSR1RAB9AL3MBTL1 | |
| SCHEMBL21572168 | 0.89 | NPSR1 (0.37) | HPGDLMNANPSR1RAB9AL3MBTL1 | |
| SCHEMBL20084119 | 0.85 | HPGD (0.35) | HPGDLMNANPSR1RAB9AL3MBTL1 | |
| SCHEMBL21572148 | 0.83 | HPGD (0.34) | HPGDLMNANPSR1RAB9AL3MBTL1 | |
| SCHEMBL20084063 | 0.82 | RAB9A (0.38) | HPGDLMNANPSR1RAB9AL3MBTL1 | |
| SCHEMBL20084029 | 0.82 | HPGD (0.34) | HPGDLMNANPSR1RAB9AL3MBTL1 | |
| SCHEMBL20084284 | 0.81 | ALDH1A1 (0.33) | HPGDLMNAALDH1A1MAPTMEN1 | |
| SCHEMBL20084354 | 0.81 | HPGD (0.38) | HPGDLMNANPSR1RAB9AL3MBTL1 | |
| SCHEMBL21572131 | 0.80 | HPGD (0.33) | HPGDLMNANPSR1RAB9AL3MBTL1 | |
| SCHEMBL20084024 | 0.80 | HPGD (0.34) | HPGDLMNANPSR1RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3312172-B1 | AMINOPYRAZOLE DERIVATIVES USEFUL AS SRC KINASE INHIBITORS | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2020-05-06 | — | — | EP | disclosed |
| EP-3312172-A1 | AMINOPYRAZOLE DERIVATIVES | Chugai Seiyaku Kabushiki Kaisha (JP) | 2018-04-25 | — | — | EP | disclosed |