SCHEMBL20086150

SCHEMBL20086150

Cc1ccc2c(c1)c1cc(C#N)cc3c4cc(-n5c6ccccc6c6ccccc65)ccc4n2c13

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGER4 P35408 2/20 0.35
KDM4E B2RXH2 2/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
ATM Q13315 1/20 0.34
MAPT P10636 2/20 0.34
ALDH1A1 P00352 1/20 0.34
HPGD P15428 1/20 0.34
CASP1 P29466 1/20 0.34
HSD17B10 Q99714 1/20 0.34
USP14 P54578 3/20 0.33
RORC P51449 5/20 0.33
TP53 P04637 1/20 0.32
BCHE P06276 1/20 0.32
ACHE P22303 1/20 0.32
F2 P00734 1/20 0.31
PLAU P00749 1/20 0.31
ELANE P08246 1/20 0.31
CTRB1 P17538 1/20 0.31
PGR P06401 1/20 0.31
RORA P35398 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20086154 0.92 KDM4E (0.40) PTGER4KDM4EL3MBTL1ATMMAPT
SCHEMBL20086152 0.92 KDM4E (0.40) PTGER4KDM4EL3MBTL1ATMMAPT
SCHEMBL20086172 0.90 KDM4E (0.38) PTGER4KDM4EL3MBTL1ATMALDH1A1
SCHEMBL20089669 0.87 KDM4E (0.38) PTGER4KDM4EL3MBTL1ATMALDH1A1
SCHEMBL16621650 0.86 KDM4E (0.43) KDM4EL3MBTL1ATMMAPTALDH1A1
SCHEMBL20086148 0.85 KDM4E (0.36) PTGER4KDM4EL3MBTL1ATMMAPT
SCHEMBL20089851 0.84 KDM4E (0.40) PTGER4KDM4EL3MBTL1ATMMAPT
SCHEMBL20086159 0.84 KDM4E (0.40) PTGER4KDM4EL3MBTL1ATMMAPT
SCHEMBL25639025 0.84 KDM4E (0.42) KDM4EL3MBTL1ATMMAPTALDH1A1
SCHEMBL18055758 0.84 BCHE (0.42) PTGER4KDM4EL3MBTL1MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180114924-A1 DELAYED FLUORESCENCE MATERIAL AND ORGANIC LIGHT EMITTING DEVICE HAVING THE DELAYED FLUORESCENCE MATERIAL Research & Business Foundation Sungkyunkwan University (KR) 2018-04-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180114924-A1 DELAYED FLUORESCENCE MATERIAL AND ORGANIC LIGHT EMITTING DEVICE HAVING THE DELAYED FLUORESCENCE MATERIAL GFPT1, ETFA, TFEB PTGER4 4130/4885KDM4E 2968/4885L3MBTL1 572/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.