Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.54 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.52 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.52 |
| ▸ | CACNG2 | Q9Y698 | 1/20 | 0.52 |
| ▸ | MAPK10 | P53779 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.46 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14505892 | 0.92 | MAPK10 (0.54) | ESR1ESR2GRIA1CACNG8CACNG2 | |
| SCHEMBL14505891 | 0.91 | MAPK10 (0.54) | ESR1ESR2GRIA1CACNG8CACNG2 | |
| SCHEMBL10023592 | 0.90 | MAPK10 (0.53) | ESR1ESR2GRIA1CACNG8CACNG2 | |
| SCHEMBL20091329 | 0.90 | ESR1 (0.66) | ESR1ESR2GRIA1CACNG8CACNG2 | |
| SCHEMBL12624739 | 0.89 | ESR1 (0.61) | ESR1ESR2GRIA1CACNG8CACNG2 | |
| SCHEMBL15172041 | 0.88 | ESR1 (0.51) | ESR1ESR2GRIA1CACNG8CACNG2 | |
| SCHEMBL14378356 | 0.88 | ESR2 (0.55) | ESR1ESR2GRIA1CACNG8CACNG2 | |
| SCHEMBL13231714 | 0.88 | ESR2 (0.67) | ESR1ESR2GRIA1CACNG8CACNG2 | |
| SCHEMBL29465993 | 0.87 | ESR1 (0.52) | ESR1ESR2GRIA1CACNG8CACNG2 | |
| SCHEMBL15172040 | 0.86 | ESR1 (0.49) | ESR1ESR2GRIA1CACNG8CACNG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10730812-B2 | Double spiro compound and organic light-emitting element comprising same | LG CHEM, LTD. (KR) | 2020-08-04 | — | — | US | disclosed |
| US-20180111887-A1 | DOUBLE SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME | LG CHEM, LTD. (KR) | 2018-04-26 | — | — | US | disclosed |
| US-20180111887-A1 | DOUBLE SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME | LG CHEM, LTD. (KR) | 2018-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10730812-B2 | Double spiro compound and organic light-emitting element comprising same | NR2E3, CRY1, CRY2 | ESR1 11/4885ESR2 17/4885GRIA1 1208/4885 |
| US-20180111887-A1 | DOUBLE SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME | NR2E3, CRY1, CRY2 | ESR1 11/4885ESR2 17/4885GRIA1 1208/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.