SCHEMBL2008746

SCHEMBL2008746

O=c1[nH]c2ccccc2cc1-c1ccccc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDR P35968 2/20 0.68
CHEK1 O14757 1/20 0.68
CDK5 Q00535 6/20 0.61
CDK5R1 Q15078 6/20 0.61
PDGFRB P09619 1/20 0.58
FGFR1 P11362 1/20 0.58
BRD4 O60885 1/20 0.56
DAO P14920 1/20 0.56
DDO Q99489 1/20 0.56
GRIN2D O15399 1/20 0.55
GRIN3B O60391 1/20 0.55
GRIN1 Q05586 1/20 0.55
GRIN2A Q12879 1/20 0.55
GRIN2B Q13224 1/20 0.55
GRIN2C Q14957 1/20 0.55
GRIN3A Q8TCU5 1/20 0.55
NPC1 O15118 3/20 0.55
RAB9A P51151 3/20 0.55
MEN1 O00255 1/20 0.54
KMT2A Q03164 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29712353 1.00 KDR (0.68) KDRCHEK1CDK5CDK5R1PDGFRB
SCHEMBL8481746 0.89 KDR (0.59) KDRCHEK1CDK5CDK5R1PDGFRB
SCHEMBL30740090 0.86 KDM4E (0.60) KDRCHEK1CDK5CDK5R1PDGFRB
SCHEMBL5543795 0.86 KDR (0.60) KDRCHEK1CDK5CDK5R1PDGFRB
SCHEMBL29206326 0.86 BRD4 (0.64) KDRCHEK1CDK5CDK5R1PDGFRB
SCHEMBL11178624 0.86 KDM4E (0.60) KDRCHEK1CDK5CDK5R1PDGFRB
SCHEMBL30740091 0.86 KDR (0.60) KDRCHEK1CDK5CDK5R1PDGFRB
SCHEMBL11347026 0.86 CDK5 (0.65) KDRCHEK1CDK5CDK5R1PDGFRB
SCHEMBL3963947 0.86 CDK5 (0.68) KDRCHEK1CDK5CDK5R1PDGFRB
SCHEMBL29206332 0.85 KDR (0.55) KDRCHEK1CDK5CDK5R1PDGFRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 182 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4644376-A1 NEW PHENYLQUINOLONE COMPOUND HAVING ANTIBACTERIAL AND ANTI-CANCER FUNCTIONS AND PREPARATION THEREOF Alphamol Science Ltd (Shanghai) (CN) 2025-11-05 EP claimed
EP-4644391-A1 NOVEL PHENYLQUINOLONE COMPOUND HAVING ANTIBACTERIAL AND ANTICANCER FUNCTIONS, AND PREPARATION THEREOF Alphamol Science Ltd (Shanghai) (CN) 2025-11-05 EP claimed
WO-2024138292-A1 NOVEL PHENYLQUINOLONE COMPOUND HAVING ANTIBACTERIAL AND ANTICANCER FUNCTIONS, AND PREPARATION THEREOF 深圳阿尔法分子科技有限责任公司 2024-07-04 WO claimed
WO-2024141126-A1 NEW PHENYLQUINOLONE COMPOUND HAVING ANTIBACTERIAL AND ANTI-CANCER FUNCTIONS AND PREPARATION THEREOF 深圳阿尔法分子科技有限责任公司 2024-07-04 WO claimed
CN-118255716-A Novel phenyl quinolone compound with antibacterial and anticancer functions and preparation thereof 深圳阿尔法分子科技有限责任公司 2024-06-28 CN claimed
EP-4046638-A1 USE OF PHENYLQUINOLINONES AND FLAVONOID DERIVATIVES FOR TREATING NEUROPATHIC PAIN Hangzhou Bio-Sincerity Pharma-tech Co., Ltd. (CN) 2022-08-24 EP claimed
EP-2686438-B1 A METHOD OF ANALYZING CHROMOSOMAL TRANSLOCATIONS AND A SYSTEM THEREFOR VENTANA MED SYST INC (US) 2018-04-18 EP claimed
US-9562259-B2 Method of analyzing chromosomal inversions VENTANA MEDICAL SYSTEMS, INC. (US) 2017-02-07 US claimed
EP-2686438-A1 A METHOD OF ANALYZING CHROMOSOMAL TRANSLOCATIONS AND A SYSTEM THEREFORE Ventana Medical Systems, Inc. (US) 2014-01-22 EP claimed
EP-2539355-A1 POLYTAG PROBES Ventana Medical Systems, Inc. (US) 2013-01-02 EP claimed
EP-2539466-A1 CYTOGENIC ANALYSIS OF METAPHASE CHROMOSOMES Ventana Medical Systems, Inc. (US) 2013-01-02 EP claimed
US-20120301885-A1 CYTOGENIC ANALYSIS OF METAPHASE CHROMOSOMES TANG LEI (US) 2012-11-29 US claimed
US-20120301886-A1 POLYTAG PROBES VENTANA MEDICAL SYSTEMS, INC. 2012-11-29 US claimed
US-20120237930-A1 METHOD OF ANALYZING CHROMOSOMAL TRANSLOCATIONS AND A SYSTEM THEREFORE VENTANA MEDICAL SYSTEMS, INC. 2012-09-20 US claimed
WO-2012123387-A1 A METHOD OF ANALYZING CHROMOSOMAL TRANSLOCATIONS AND A SYSTEM THEREFORE F. HOFFMANN-LA ROCHE AG (CH) 2012-09-20 WO claimed
EP-0073875-B1 AZO DYESTUFFS, PROCESS FOR THEIR PREPARATION AND THEIR USE CASSELLA Aktiengesellschaft (DE) 1988-09-07 EP claimed
JP-3024047-A None JP disclosed
US-12587724-B2 Digitally enhanced microscopy for multiplexed histology VENTANA MEDICAL SYSTEMS, INC. (US) 2026-03-24 US disclosed
US-4008086-A PYRIDONE OR PYRIDAZONE DERIVATIVES KONISHIROKU PHOTO INDUSTRY CO., LTD. (JA) 1977-02-15 US disclosed
US-4006148-A Carbostyril derivatives used as coccidiostats IMC CHEMICAL GROUP, INC. (US) 1977-02-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12587724-B2 Digitally enhanced microscopy for multiplexed histology MAP1LC3B, MAP1LC3A, MAP1LC3C KDR 506/4885CHEK1 1265/4885CDK5 1657/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.